National Center for Veterans Studies, The University of Utah.
J Clin Psychol. 2018 Dec;74(12):2070-2081. doi: 10.1002/jclp.22651. Epub 2018 Jun 19.
This study aimed to examine the effectiveness of cognitive processing therapy (CPT) for posttraumatic stress disorder (PTSD) when administered on a daily basis during a 2-week period of time.
In an open-label, prospective cohort pilot trial, 20 U.S. military personnel and veterans diagnosed with PTSD or subthreshold PTSD participated in 12 daily sessions of CPT. Primary outcomes included Clinician Administered PTSD Scale for DSM-5 and PTSD Checklist for DSM-5 scores. Secondary outcomes included Patient Health Questionnaire-8 and Beck Scale for Suicide Ideation (BSSI) scores. Interviews and self-report scales were completed at pretreatment, posttreatment, and 6 months after the treatment.
Relative to baseline, PTSD symptom severity and rates of PTSD diagnosis were significantly reduced at posttreatment and 6-month follow-up. Depression symptom severity did not significantly improve, but suicide ideation significantly decreased at 6-month follow-up.
Daily administration of CPT is associated with significant reductions in PTSD and suicide ideation.
本研究旨在考察创伤后应激障碍（PTSD）认知加工疗法（CPT）在 2 周时间内每日治疗时的有效性。
在一项开放标签、前瞻性队列试验中，20 名美国军人和退伍军人被诊断为 PTSD 或阈下 PTSD，参加了 12 次每日 CPT 治疗。主要结局包括 DSM-5 创伤后应激障碍量表和 DSM-5 创伤后应激障碍检查表评分。次要结局包括患者健康问卷-8 和贝克自杀意念量表（BSSI）评分。访谈和自我报告量表在治疗前、治疗后和治疗后 6 个月进行评估。
与基线相比，治疗后和 6 个月随访时 PTSD 症状严重程度和 PTSD 诊断率显著降低。抑郁症状严重程度没有显著改善，但自杀意念在 6 个月随访时显著降低。
CPT 的每日给药与 PTSD 和自杀意念的显著减少有关。
