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下尿路症状(LUTS)患者勃起功能障碍与LUTS严重程度及临床特征的相关性分析

Correlation Analysis of Erectile Dysfunction with Lower Urinary Tract Symptoms (LUTS) Degree and Clinical Features in LUTS Patients.

作者信息

Wang Lei, Wang Tongqing, Liu Jian, Wang Jizheng

机构信息

Dept. of Urology, Ward 1, Zhengzhou Central Hospital Affiliated to Zhengzhou University, Zhengzhou 450007, Henan Province, China.

出版信息

Iran J Public Health. 2018 May;47(5):658-665.

Abstract

BACKGROUND

We aimed to investigate the prevalence of erectile dysfunction (ED) in patients with lower urinary tract symptoms (LUTS) and to explore the correlation of ED with LUTS and its clinical features.

METHODS

Overall, 400 outpatients and inpatients with LUTS diagnosed in Zhengzhou Central Hospital, Zhengzhou University, Zhengzhou, Henan Province, China from June 2015 to June 2017 were collected. LUTS degree was assessed by the International Prostate Symptom Score (IPSS), and ED degree was assessed by the International Index of Erectile Function (IIEF-5). The correlation of ED with LUTS degree, age, blood lipids, homocysteine (Hcy) and other factors was analyzed.

RESULTS

The prevalence of ED in patients with LUTS was 82.25%. With the increase in age, the prevalence of ED was significantly elevated, and ED degree gradually became higher (<0.01). The higher the degree of LUTS was, the higher the prevalence of ED would be. The degree of ED was highly correlated with the combination with hypertension, diabetes mellitus and coronary heart disease (<0.05). The prevalence of ED was positively correlated with LUTS degree and the levels of total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C) and Hcy (<0.05 or <0.01).

CONCLUSION

ED prevalence of patients with LUTS is high, and ED is significantly related to LUTS degree, age and the levels of TC, LDL-C and Hcy in patients with LUTS.

摘要

背景

我们旨在调查下尿路症状(LUTS)患者勃起功能障碍(ED)的患病率,并探讨ED与LUTS及其临床特征的相关性。

方法

总体而言,收集了2015年6月至2017年6月在中国河南省郑州市郑州大学附属郑州中心医院诊断为LUTS的400例门诊和住院患者。通过国际前列腺症状评分(IPSS)评估LUTS程度,通过国际勃起功能指数(IIEF-5)评估ED程度。分析ED与LUTS程度、年龄、血脂、同型半胱氨酸(Hcy)及其他因素的相关性。

结果

LUTS患者中ED的患病率为82.25%。随着年龄的增加,ED的患病率显著升高,且ED程度逐渐加重(<0.01)。LUTS程度越高,ED的患病率越高。ED程度与合并高血压、糖尿病和冠心病显著相关(<0.05)。ED的患病率与LUTS程度以及总胆固醇(TC)、低密度脂蛋白胆固醇(LDL-C)和Hcy水平呈正相关(<0.05或<0.01)。

结论

LUTS患者中ED的患病率较高,且ED与LUTS程度、年龄以及LUTS患者的TC、LDL-C和Hcy水平显著相关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d24/6005987/8ac5b61c4aa8/IJPH-47-658-g001.jpg

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