Kim Hyeongtae, Kim Wonhee, Kang Gu Hyun, Jang Yong Soo, Choi Hyun Young, Kim Jae Guk, Kim In Young, Kim Minji
Department of Emergency Medicine, College of Medicine, Hallym University, Seoul, Republic of Korea Department of Biomedical Engineering, College of Medicine, Hanyang University, Seoul, Republic of Korea.
Medicine (Baltimore). 2018 Jun;97(25):e10918. doi: 10.1097/MD.0000000000010918.
Leukosan SkinLink (LS), which combines non-woven textile strips and tissue adhesive, offers the advantage of atraumatic treatment while effectively shortening the procedure time. We hypothesized that wound closure would be faster with LS than with surgical suture (SS) and the wound infection and dehiscence would be similar.
A prospective, open label, single-center, randomized controlled trial was performed. Between November 2014 and April 2016, 49 patients with traumatic lacerations who presented to the emergency department were eligible for study inclusion.
The mean wound closure time was significantly lower in the LS group than in the SS group (1.48 ± 0.2 seconds vs 8.8 ± 3.6 minutes, P < .001). After adjusting the wound closure time according to the lacerations length, the time remained significantly lower in the LS group than in the SS group (1.0 ± 0.8 seconds vs 5.03 ± 2.5minutes, P < .001). During follow-up for 14 days, no significant differences in dehiscence and wound infection were observed between the 2 groups.
Wound closure was approximately 4minutes faster with LS and there were no differences in wound infection and dehiscence rates. Thus, the LS could be used as a timesaving suture technique for acute traumatic lacerations in emergency department (ED).
ClinicalTrials.gov NCT02333877.
Leukosan SkinLink（LS）结合了无纺布条和组织粘合剂，具有无创治疗的优势，同时能有效缩短手术时间。我们假设，与手术缝线（SS）相比，使用LS闭合伤口的速度更快，且伤口感染和裂开情况相似。
进行了一项前瞻性、开放标签、单中心、随机对照试验。在2014年11月至2016年4月期间，49例因创伤性撕裂伤就诊于急诊科的患者符合纳入研究的条件。
LS组的平均伤口闭合时间显著低于SS组（1.48±0.2秒对8.8±3.6分钟，P<0.001）。根据撕裂伤长度调整伤口闭合时间后，LS组的时间仍显著低于SS组（1.0±0.8秒对5.03±2.5分钟，P<0.001）。在14天的随访期间，两组在裂开和伤口感染方面未观察到显著差异。
使用LS闭合伤口的速度快约4分钟，且伤口感染率和裂开率无差异。因此，LS可作为急诊科急性创伤性撕裂伤的一种节省时间的缝合技术。
ClinicalTrials.gov NCT02333877。
