Song Chunhua, Li Wei, Leng Junhong, Wang Leishen, Li Weiqin, Shi Fenglan, Liu Guifeng, Zhou Juan, Yang Xilin
a Department of Epidemiology and Biostatistics, School of Public Health , Tianjin Medical University , Tianjin , China.
b Center for Disease Control and Prevention of Tianjin Economic-Technological Development Area (TEDA) , Tianjin , China.
Women Health. 2019 Mar;59(3):281-293. doi: 10.1080/03630242.2018.1478365. Epub 2018 Aug 17.
Smoking has been associated with depression in the general population. Whether passive smoking is also associated with postpartum depression (PPD) is uncertain. From 2010 to 2012, we recruited 8,842 pregnant women in Tianjin, China. The mainland Chinese version of the Edinburgh Postnatal Depression Scale was used to evaluate postpartum depressive symptoms after birth, with a score of >9 defining PPD. Data were collected using specially designed questionnaires or data from the electronic database of Tianjin Maternal and Child Health Information System. Odds ratios (OR) and 95 percent confidence intervals (CI) were obtained for the association of smoking status with PPD using binary logistic regression. Passive smoke exposure rates before and during pregnancy were 40.9 percent and 52.1 percent, respectively. A total of 8.5% (n = 747) of participants had PPD. Compared with those not exposed, women passively exposed to smoke before and during pregnancy had higher odds of PPD (before pregnancy: OR: 1.24, 95 percent CI: 1.03-1.50; during pregnancy: OR: 1.43, 95 percent CI: 1.16-1.77) after adjustment for confounding factors. Passive smoking before and during pregnancy were associated with PPD in Chinese women. Reducing passive smoke exposure may reduce PPD in Chinese women; further longitudinal studies are warranted to replicate these findings.
在普通人群中，吸烟与抑郁症有关。被动吸烟是否也与产后抑郁症（PPD）有关尚不确定。2010年至2012年，我们在中国天津招募了8842名孕妇。使用中文版爱丁堡产后抑郁量表评估产后抑郁症状，得分>9分定义为产后抑郁症。通过专门设计的问卷或天津妇幼健康信息系统电子数据库中的数据收集资料。使用二元逻辑回归分析得出吸烟状况与产后抑郁症之间关联的比值比（OR）和95%置信区间（CI）。孕期前和孕期被动吸烟暴露率分别为40.9%和52.1%。共有8.5%（n = 747）的参与者患有产后抑郁症。在对混杂因素进行调整后，与未暴露者相比，孕期前和孕期被动吸烟的女性患产后抑郁症的几率更高（孕期前：OR：1.24，95%置信区间：1.03 - 1.50；孕期：OR：1.43，95%置信区间：1.16 - 1.77）。孕期前和孕期被动吸烟与中国女性产后抑郁症有关。减少被动吸烟暴露可能会降低中国女性产后抑郁症的发病率；有必要进行进一步的纵向研究以重复这些发现。
