Günther T, Vormann J
Biochem Biophys Res Commun. 1985 Jul 31;130(2):540-5. doi: 10.1016/0006-291x(85)90450-4.
Mg2+ efflux from Mg2+-preloaded chicken erythrocytes is caused by an electroneutral Na+/Mg2+ antiport. It depends specifically on extracellular Na+, according to Michaelis-Menten kinetics (Km = 25 mM), and is reversibly noncompetitively inhibited by amiloride (Ki = 0.59 mM). In contrast to Na+/H+ antiport, Li+, Ca2+ and N-ethylmaleimide do not interfere with Na+/Mg2+ antiport. The Na+/Mg2+ antiport is driven by the intracellular/extracellular Mg2+ gradient.
镁离子预负载的鸡红细胞中镁离子外流是由电中性的钠/镁反向转运体引起的。根据米氏动力学（Km = 25 mM），它特别依赖于细胞外钠离子，并且被氨氯吡咪可逆性非竞争性抑制（Ki = 0.59 mM）。与钠/氢反向转运体不同，锂离子、钙离子和N-乙基马来酰亚胺不会干扰钠/镁反向转运体。钠/镁反向转运体由细胞内/细胞外镁离子梯度驱动。
