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光触发的 MOF 药物输送载体中 5-氟尿嘧啶的释放。

Photo-triggered release of 5-fluorouracil from a MOF drug delivery vehicle.

机构信息

Department of Chemistry and Macromolecules Innovation Institute, Virginia Tech, Blacksburg, VA 24060, USA.

出版信息

Chem Commun (Camb). 2018 Jul 5;54(55):7617-7620. doi: 10.1039/c8cc01601a.

DOI:10.1039/c8cc01601a
PMID:29926872
Abstract

A nano metal-organic-framework (nanoMOF) was employed as a first-of-its kind drug delivery vehicle (DDV) for the photo-controlled release of therapeutics with simultaneous breakdown of the carrier into small molecules.

摘要

一种纳米金属-有机骨架(nanoMOF)被首次用作药物输送载体(DDV),用于光控释放治疗药物,同时载体分解为小分子。

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