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坏死性筋膜炎作为免疫功能正常儿童原发性水痘感染的一种并发症。

Necrotising fasciitis as a complication of primary varicella infection in an immunocompetent child.

作者信息

Darmasseelane Karthik, Banks Teresa, Rjabova Tatiana

机构信息

Department of Paediatrics, Royal United Hospitals Bath NHS Foundation Trust, Bath, UK.

出版信息

BMJ Case Rep. 2018 Jun 21;2018:bcr-2018-225018. doi: 10.1136/bcr-2018-225018.

DOI:10.1136/bcr-2018-225018
PMID:29930190
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6020885/
Abstract

Necrotising fasciitis (NF) is an infrequent yet significant complication of primary varicella infection in immunocompetent children. We report a case of a 4-year-old girl who presented three days into her chicken pox illness, with a rapidly progressing, severely tender erythematous rash surrounding one chicken pox lesion on her thigh. She required intravenous antibiotics, two surgical debridements, a skin graft and a prolonged stay in the paediatric intensive care unit, but ultimately we were able to save her life and limb. NF is a rare complication of chicken pox that has high morbidity and mortality that requires prompt and specific treatment.

摘要

坏死性筋膜炎(NF)是免疫功能正常儿童原发性水痘感染中一种罕见但严重的并发症。我们报告一例4岁女孩,她在水痘发病三天后出现大腿上一个水痘皮疹周围迅速进展、严重压痛的红斑疹。她需要静脉注射抗生素、两次手术清创、一次皮肤移植,并在儿科重症监护病房长期住院,但最终我们成功挽救了她的生命和肢体。NF是水痘的一种罕见并发症,具有高发病率和死亡率,需要及时、特异性治疗。

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Necrotising fasciitis as a complication of primary varicella infection in an immunocompetent child.坏死性筋膜炎作为免疫功能正常儿童原发性水痘感染的一种并发症。
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引用本文的文献

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A systematic review of necrotising fasciitis in children from its first description in 1930 to 2018.对 1930 年首例坏死性筋膜炎描述以来儿童坏死性筋膜炎的系统回顾。
BMC Infect Dis. 2019 Apr 11;19(1):317. doi: 10.1186/s12879-019-3941-3.

本文引用的文献

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The burden of hospitalisation for varicella and herpes zoster in England from 2004 to 2013.2004 年至 2013 年期间英国水痘和带状疱疹住院负担。
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Epidemiology and outcome of necrotizing fasciitis in children: an active surveillance study of the Canadian Paediatric Surveillance Program.儿童坏死性筋膜炎的流行病学与转归:加拿大儿科监测项目的一项主动监测研究
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Necrotizing fasciitis: report of 39 pediatric cases.坏死性筋膜炎:39例儿科病例报告
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