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习惯性热水浴可保护中年至老年日本受试者的心血管功能。

Habitual hot water bathing protects cardiovascular function in middle-aged to elderly Japanese subjects.

机构信息

Faculty of Collaborative Regional Innovation, Ehime University, Ehime, Matsuyama, Japan.

Center for Genomic Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan.

出版信息

Sci Rep. 2018 Jun 21;8(1):8687. doi: 10.1038/s41598-018-26908-1.

Abstract

Favorable effects of sauna bathing on cardiovascular disease have been demonstrated. Hot water bathing is an alternative, and could also have similar effects. Information pertaining to hot water bathing frequency and water temperature was obtained from 873 subjects. Carotid mean and max intima-media thickness (IMT) and brachial-ankle pulse wave velocity (baPWV) were measured as indices of atherosclerosis. Central haemodynamics were evaluated using radial pulse waveform analyses. Plasma levels of B-type natriuretic peptide (BNP) were measured as an index for cardiac loading. The mean duration of a single hot bath was 12.4 ± 9.9 min. Subject bathing in hot water ≥5 times per week had significantly lower baPWV, central pulse pressure (PP), and BNP after correcting for possible confounding parameters. Stepwise regression analyses revealed that hot water temperature was negatively associated with baPWV, while bathing frequency was negatively related to central PP and BNP. A longitudinal follow-up in 164 subjects showed that hot water bathing ≥5 times per week was associated with significantly lower increase in BNP over time, while the temperature of the water tended to be related to lower increases in carotid max IMT and baPWV. Hot water bathing showed a favorable effect on atherosclerotic and central haemodynamic parameters.

摘要

洗桑拿浴对心血管疾病有有益影响。热水浴是另一种选择,也可能有类似的效果。从 873 名受试者中获得了与热水浴频率和水温相关的信息。颈动脉平均和最大内膜中层厚度(IMT)和肱踝脉搏波速度(baPWV)被用作动脉粥样硬化的指标。使用桡动脉脉搏波分析评估中心血液动力学。测量 B 型利钠肽(BNP)的血浆水平作为心脏负荷的指标。单次热水浴的平均持续时间为 12.4±9.9 分钟。在纠正可能的混杂参数后,每周洗热水澡≥5 次的受试者的 baPWV、中心脉搏压(PP)和 BNP 显著降低。逐步回归分析显示,热水温度与 baPWV 呈负相关,而洗澡频率与中心 PP 和 BNP 呈负相关。在 164 名受试者的纵向随访中,每周洗热水澡≥5 次与 BNP 随时间的显著降低有关,而水温与颈动脉最大 IMT 和 baPWV 的升高呈负相关。热水浴对动脉粥样硬化和中心血液动力学参数有有益的影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/23b4/6013438/50cca87e5573/41598_2018_26908_Fig1_HTML.jpg

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