Lim Yong-Hyun, Kim Ji-Soo, Lee Ho-Won, Kim Sung-Hee
Department of Neurology, Kyungpook National University School of Medicine, Kyungpook National University Chilgok Hospital, Daegu, South Korea.
Department of Neurology, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seoul, South Korea.
Front Neurol. 2018 Jun 7;9:433. doi: 10.3389/fneur.2018.00433. eCollection 2018.
Patients with vestibular migraine are susceptible to motion sickness. This study aimed to determine whether the severity of posture instability is related to the susceptibility to motion sickness. We used a visual motion paradigm with two conditions of the stimulated retinal field and the head posture to quantify postural stability while maintaining a static stance in 18 patients with vestibular migraine and in 13 age-matched healthy subjects. Three parameters of postural stability showed differences between VM patients and controls: RMS velocity (0.34 ± 0.02 cm/s vs. 0.28 ± 0.02 cm/s), RMS acceleration (8.94 ± 0.74 cm/s vs. 6.69 ± 0.87 cm/s), and sway area (1.77 ± 0.22 cm vs. 1.04 ± 0.25 cm). Patients with vestibular migraine showed marked postural instability of the head and neck when visual stimuli were presented in the retinal periphery. The pseudo-Coriolis effect induced by head roll tilt was not responsible for the main differences in postural instability between patients and controls. Patients with vestibular migraine showed a higher visual dependency and low stability of the postural control system when maintaining quiet standing, which may be related to susceptibility to motion sickness.
前庭性偏头痛患者易患晕动病。本研究旨在确定姿势不稳的严重程度是否与晕动病易感性相关。我们采用一种视觉运动范式，通过刺激视网膜区域和头部姿势的两种条件，在18例前庭性偏头痛患者和13例年龄匹配的健康受试者保持静态站立时量化姿势稳定性。姿势稳定性的三个参数在前庭性偏头痛患者和对照组之间存在差异：均方根速度（0.34±0.02cm/s对0.28±0.02cm/s）、均方根加速度（8.94±0.74cm/s对6.69±0.87cm/s）和摆动面积（1.77±0.22cm对1.04±0.25cm）。当前庭性偏头痛患者视网膜周边出现视觉刺激时，其头颈部姿势不稳明显。头部侧倾诱发的伪科里奥利效应并非患者与对照组姿势不稳主要差异的原因。前庭性偏头痛患者在保持安静站立时表现出更高的视觉依赖性和姿势控制系统的低稳定性，这可能与晕动病易感性有关。
