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红茶可提高秀丽隐杆线虫的高渗应激抗性。

Black tea increases hypertonic stress resistance in C. elegans.

机构信息

National Research Center of Engineering Technology for Utilization of Functional Ingredients from Botanicals, Hunan Agricultural University, Changsha, Hunan 410128, China.

出版信息

Food Funct. 2018 Jul 17;9(7):3798-3806. doi: 10.1039/c7fo02017a.

DOI:10.1039/c7fo02017a
PMID:29932178
Abstract

Here we identified that BTE (black tea extract), within the studied concentration range, is more effective than GTE (green tea extract) in protecting C. elegans against hypertonic stress, by enhancing survival after exposure to various salts, and alleviating suffered motility loss and body shrinkage. The mechanism of such protection may be due to the ability of black tea to induce the conserved WNK/GCK signaling pathway and down-regulation of the expression levels of nlp-29. Intriguingly, black tea does not relieve hypertonicity-induced protein damage. The findings implicate the potential health benefits of black tea consumed worldwide.

摘要

在这里,我们发现 BTE(红茶提取物)在研究的浓度范围内比 GTE(绿茶提取物)更有效,能够通过增强暴露于各种盐后的生存能力并减轻运动能力丧失和身体收缩来保护秀丽隐杆线虫免受高渗应激。这种保护的机制可能是由于红茶能够诱导保守的 WNK/GCK 信号通路并下调 nlp-29 的表达水平。有趣的是,红茶不能缓解高渗诱导的蛋白质损伤。这些发现暗示了全球范围内饮用红茶的潜在健康益处。

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