Postgraduate Program in Physiotherapy, Department of Physiotherapy, Faculdade de Ciências e Tecnologia, Univ Estadual Paulista, Presidente Prudente, Brazil; and.
Laboratory of Phototherapy in Sports and Exercise, Postgraduate Program in Rehabilitation Sciences, Nove de Julho University São Paulo, Brazil.
Clin J Sport Med. 2020 May;30(3):267-274. doi: 10.1097/JSM.0000000000000606.
The main focus of this systematic review was to determine the efficacy of phototherapy in the management of creatine kinase (CK) activity after exercise and furthermore to identify for which exercise model protocol phototherapy provides the best results.
Meta-analysis comparing phototherapy with a control condition.
The MEDLINE, EMBASE, SPORTDiscus, PEDro, and CENTRAL databases were searched from their earliest records to October 03, 2016. Data were pooled in a meta-analysis and described as standardized mean difference (SMD) with 95% confidence intervals (CIs) using a random effects model.
Healthy subjects (no restrictions were applied, eg, age, sex, and exercise level).
Phototherapy (low-level laser therapy and/or light-emitting diode therapy) before or after exercise and a placebo or control condition.
Creatine kinase activity (no restriction to any analysis, eg, serum, plasma, or capillary blood).
Fourteen studies were included for review. The results revealed that phototherapy has a more positive effect than control condition in management of CK activity [SMD = 0.77, 95% CI (0.32 to 1.22); P = 0.0007; I = 72%]. In exploratory analysis, the results showed that phototherapy was effective only in the exercise protocol with localized exercise with large effect size [localized exercise: SMD = 0.89, 95% CI (0.26 to 1.51); P = 0.0002; I = 76%; general exercise: SMD = 0.61, 95% CI (-0.05 to 1.26); P = 0.07; I = 67%].
The available evidence suggest that phototherapy has beneficial effects on the management of CK activity and demonstrate a possible relationship based on damage caused by exercise, providing a greater effect in studies that used localized exercise.
本系统评价的主要重点是确定光疗在运动后肌酸激酶（CK）活性管理中的疗效，并进一步确定哪种运动模型方案的光疗效果最佳。
比较光疗与对照条件的荟萃分析。
从最早记录开始，在 2016 年 10 月 03 日之前，在 MEDLINE、EMBASE、SPORTDiscus、PEDro 和 CENTRAL 数据库中进行了搜索。使用随机效应模型，将数据汇总到荟萃分析中，并以标准化均数差（SMD）和 95%置信区间（CI）表示。
健康受试者（无任何限制，例如年龄、性别和运动水平）。
运动前后的光疗（低水平激光治疗和/或发光二极管治疗）和安慰剂或对照条件。
肌酸激酶活性（无任何分析限制，例如血清、血浆或毛细血管血）。
纳入了 14 项研究进行综述。结果表明，光疗对 CK 活性的管理效果优于对照条件[SMD=0.77，95%CI（0.32 至 1.22）；P=0.0007；I=72%]。在探索性分析中，结果表明，光疗仅在局部运动的运动方案中有效，且效果较大[局部运动：SMD=0.89，95%CI（0.26 至 1.51）；P=0.0002；I=76%；一般运动：SMD=0.61，95%CI（-0.05 至 1.26）；P=0.07；I=67%]。
现有证据表明，光疗对 CK 活性的管理具有有益的影响，并基于运动引起的损伤显示出一种可能的关系，在使用局部运动的研究中效果更大。
