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圆锥角膜中霍拉戴等效角膜曲率计读数与角膜前表面角膜曲率测量的比较。

Comparison of Holladay equivalent keratometry readings and anterior corneal surface keratometry measurements in keratoconus.

作者信息

Saglik Ayhan, Celik Hakim

机构信息

Department of Ophthalmology, Harran University Faculty of Medicine, 63300, Haliliye Şanlıurfa, Turkey.

Department of Physiology, Harran University Faculty of Medicine, Şanlıurfa, Turkey.

出版信息

Int Ophthalmol. 2019 Jul;39(7):1501-1509. doi: 10.1007/s10792-018-0967-2. Epub 2018 Jun 22.

Abstract

PURPOSE

To compare the accuracy of the anterior corneal simulated keratometry (SimK) and the Holladay equivalent keratometry reading (EKR) provided by a Scheimpflug camera (Pentacam HR) with the keratometry (K) provided by a Placido system (T-Cone topography) in keratoconus and control eyes.

METHODS

This prospective study included 40 consecutive patients with keratoconus and 40 voluntary participants with no ocular complaints. Any patients with corneal scar, corneal trauma, history of corneal surgery or contact lens usage were excluded from the study. Mean SimK and Holladay EKR measurements were taken with Pentacam HR in the 2, 3, and 4.5 mm corneal zones, and these values were compared with the T-Cone mean K value with the Placido topography system attachment on the Lenstar LS 900. Statistical analysis was performed using the paired Student's t test and the Bland-Altman analysis.

RESULTS

A statistically significant difference was determined between the Placido K and the Scheimpflug EKR 2, 3, 4.5 mm and SimK values in the keratoconus group (p < 0.05). In the analyses which showed a difference between the SimK and Holladay EKR, it was observed that as the diameter of the corneal zone increased, the 95% LoA values were extended. No statistically significant difference was determined between the SimK and EKR 2 mm values (p > 0.05). In the control group, there was no statistically significant difference between any of the keratometric values.

CONCLUSION

In diseases which affect the posterior corneal surface, such as keratoconus, it is thought that because of the asymmetrical peripheral placement of the corneal apex, as the corneal diameter increases there could be an error increase of 1-3 mm in keratometric systems evaluating the anterior surface.

摘要

目的

比较在圆锥角膜和对照眼中,由Scheimpflug相机(Pentacam HR)提供的前角膜模拟角膜曲率计测量值(SimK)和霍拉迪等效角膜曲率读数(EKR)与由Placido系统(T-Cone地形图仪)提供的角膜曲率计测量值(K)的准确性。

方法

这项前瞻性研究纳入了40例连续的圆锥角膜患者和40名无眼部不适的自愿参与者。任何有角膜瘢痕、角膜外伤、角膜手术史或佩戴隐形眼镜史的患者均被排除在研究之外。使用Pentacam HR在2、3和4.5毫米角膜区域测量平均SimK和霍拉迪EKR值,并将这些值与Lenstar LS 900上配备Placido地形图系统附件的T-Cone平均K值进行比较。采用配对t检验和Bland-Altman分析进行统计分析。

结果

在圆锥角膜组中,Placido K与Scheimpflug EKR在2、3、4.5毫米处的值以及SimK值之间存在统计学显著差异(p<0.05)。在显示SimK和霍拉迪EKR之间存在差异的分析中,观察到随着角膜区域直径的增加,95%的一致性界限值扩大。SimK和EKR在2毫米处的值之间未确定有统计学显著差异(p>0.05)。在对照组中,任何角膜曲率测量值之间均无统计学显著差异。

结论

在诸如圆锥角膜等影响角膜后表面的疾病中,由于角膜顶点在周边位置不对称,随着角膜直径增加,评估前表面的角膜曲率测量系统可能会出现1至3毫米的误差增加。

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