使用近红外光谱技术在性唤起过程中同步监测前额叶皮层和生殖器官的血流动力学反应
Simultaneous Monitoring of Hemodynamic Response in the Pre-Frontal Cortex and Genital Organ During Sexual Arousal Using Near-Infrared Spectroscopy.
作者信息
Kim Evgenii, Kim Sungchul, Zephaniah Phillips V, Lee Songhyun, Anguluan Eloise, Park Kwangsung, Kim Jae Gwan
机构信息
School of Electrical Engineering and Computer Science, Gwangju Institute of Science and Technology, Gwangju, Republic of Korea.
Department of Biomedical Science and Engineering, Gwangju Institute of Science and Technology, Gwangju, Republic of Korea.
出版信息
Sex Med. 2018 Sep;6(3):234-238. doi: 10.1016/j.esxm.2018.05.001. Epub 2018 Jun 20.
BACKGROUND
The monitoring of brain activity along with genital organ response to sexual stimulation can play an important role in understanding the under-lying mechanisms of sexual arousal as well as diagnosing erectile dysfunction. Several studies have observed brain activity corresponding to sexual stimuli, but only a few studies have shown a simultaneous measurement of brain activation and penile response.
AIM
To introduce near-infrared spectroscopy (NIRS) as a portable, easily implemented, and low-cost technique to simultaneously record brain activity and hemodynamics in the genital organ during sexual arousal.
METHODS
Hemodynamic measurements of 15 healthy men were obtained using a home-built NIRS system. In the initial experiment, hemodynamics in the pre-frontal cortex (N = 10) were measured during visual sexual stimulation (VSS) and neutral visual stimulation (NVS) to identify brain activity related to sexual arousal. In the subsequent experiment, cerebral and penile hemodynamics were simultaneously measured (N = 5) using NIRS during VSS and NVS.
RESULTS
The pre-frontal cortex showed activity related to VSS but not to NVS. Simultaneous measurements showed a corresponding increase of penile oxygenated and deoxygenated hemoglobin concentration indicating an increase of blood volume associated with sexual arousal in healthy men. An average response delay of 4 seconds was observed in the hemodynamic changes between the brain and genital organ.
CONCLUSION
In this preliminary study, we presented a NIRS system capable not only of detecting cerebral hemodynamic changes related to sexual arousal but also the simultaneous measurement of penile hemodynamics. We believe the NIRS system can be a potential technique to supplement the field of sexual medicine and can be expanded further to diagnose erectile dysfunction. Kim E, Kim S, Zephaniah PV, et al. Simultaneous Monitoring of Hemodynamic Response in the Pre-Frontal Cortex and Genital Organ During Sexual Arousal Using Near-Infrared Spectroscopy. Sex Med 2018;6:234-238.
背景
监测大脑活动以及生殖器官对性刺激的反应，对于理解性唤起的潜在机制以及诊断勃起功能障碍可能具有重要作用。多项研究观察到了与性刺激相对应的大脑活动，但仅有少数研究实现了大脑激活与阴茎反应的同步测量。
目的
引入近红外光谱技术（NIRS），这是一种便携式、易于实施且低成本的技术，用于在性唤起期间同步记录大脑活动和生殖器官的血流动力学变化。
方法
使用自行搭建的NIRS系统对15名健康男性进行血流动力学测量。在初始实验中，对10名男性在视觉性刺激（VSS）和中性视觉刺激（NVS）期间测量前额叶皮质的血流动力学，以确定与性唤起相关的大脑活动。在后续实验中，对5名男性在VSS和NVS期间使用NIRS同时测量大脑和阴茎的血流动力学。
结果
前额叶皮质显示出与VSS相关的活动，但与NVS无关。同步测量显示，阴茎中氧合血红蛋白和脱氧血红蛋白浓度相应增加，表明健康男性在性唤起时血容量增加。大脑和生殖器官的血流动力学变化之间平均观察到4秒的反应延迟。
结论
在这项初步研究中，我们展示了一种NIRS系统，它不仅能够检测与性唤起相关的大脑血流动力学变化，还能同时测量阴茎血流动力学。我们认为NIRS系统可能成为补充性医学领域的一项潜在技术，并可进一步扩展用于诊断勃起功能障碍。Kim E, Kim S, Zephaniah PV等。使用近红外光谱技术在性唤起期间同步监测前额叶皮质和生殖器官的血流动力学反应。性医学2018；6：234 - 238。
Zotero 插件