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铜绿假单胞菌烈性噬菌体的DNA同源性与吸附特异性

DNA homology and adsorption specificity of Pseudomonas aeruginosa virulent bacteriophages.

作者信息

Kulakov L A, Ksenzenko V N, Kochetkov V V, Mazepa V N, Boronin A M

出版信息

Mol Gen Genet. 1985;200(1):123-7. doi: 10.1007/BF00383324.

Abstract

The DNA homology and adsorption specificity of newly isolated virulent bacteriophages of P. aeruginosa have been studied. On the basis of this analysis all phages were divided into four groups: phi k, phi m, phi mnP78-like and phi mnF82-like bacteriophages. DNA's of phi k as well as phi m phages were shown to possess different restriction patterns although they have an extensive homology. Unlike other groups, phi k phages were characterized by the presence of T4 DNA ligase--repaired, single-chain breaks.

摘要

对新分离的铜绿假单胞菌强毒株噬菌体的DNA同源性和吸附特异性进行了研究。基于该分析,所有噬菌体被分为四组:φk、φm、类φmnP78和类φmnF82噬菌体。尽管φk和φm噬菌体的DNA具有广泛的同源性,但显示它们具有不同的限制性图谱。与其他组不同,φk噬菌体的特征是存在T4 DNA连接酶修复的单链断裂。

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