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空肠弯曲菌对27种抗菌药物以及β-内酰胺类与克拉维酸或舒巴坦的各种组合的体外敏感性。

In vitro susceptibility of Campylobacter jejuni to 27 antimicrobial agents and various combinations of beta-lactams with clavulanic acid or sulbactam.

作者信息

Van der Auwera P, Scorneaux B

出版信息

Antimicrob Agents Chemother. 1985 Jul;28(1):37-40. doi: 10.1128/AAC.28.1.37.

DOI:10.1128/AAC.28.1.37
PMID:2994557
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC176305/
Abstract

The in vitro susceptibility of human isolates of Campylobacter jejuni was investigated with 27 antibiotics and 8 combinations of beta-lactams with clavulanic acid or sulbactam. Ansamycin, the new quinolines, erythromycin, and cefpirome were the most active drugs against C. jejuni; amoxicillin, ampicillin, cefotaxime, and ceftazidime 90% of the isolates, greater than or equal to 50 mg/liter). The activity of various beta-lactams was unchanged by the addition of clavulanic acid or sulbactam.

摘要

用27种抗生素以及8种β-内酰胺类与克拉维酸或舒巴坦的组合，对空肠弯曲菌的人体分离株进行了体外药敏试验。安莎霉素、新型喹诺酮类、红霉素和头孢匹罗是对空肠弯曲菌最具活性的药物；阿莫西林、氨苄西林、头孢噻肟和头孢他啶对90%的分离株有效（大于或等于50毫克/升）。添加克拉维酸或舒巴坦后，各种β-内酰胺类的活性未发生变化。

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本文引用的文献

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Pharmacokinetics of amoxicillin and clavulanic acid administered alone and in combination.单独及联合使用阿莫西林和克拉维酸的药代动力学。
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Incidence of trimethoprim-sulfamethoxazole-resistant enterobacteriaceae among transplant recipients.移植受者中对甲氧苄啶-磺胺甲恶唑耐药的肠杆菌科细菌的发生率。
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