感觉运动 alpha 运动功率与皮质脊髓兴奋性呈正相关。
Sensorimotor mu-alpha power is positively related to corticospinal excitability.
机构信息
Department of Neurology & Stroke, and Hertie Institute for Clinical Brain Research, Eberhard Karls University of Tübingen, Hoppe-Seyler-Str. 3, 72076, Tübingen, Germany.
Department of Neurology & Stroke, and Hertie Institute for Clinical Brain Research, Eberhard Karls University of Tübingen, Hoppe-Seyler-Str. 3, 72076, Tübingen, Germany; Institute of Medical Psychology and Behavioral Neurobiology, Eberhard Karls University of Tübingen, Otfried-Müller-Straße 25, 72076, Tübingen, Germany.
出版信息
Brain Stimul. 2018 Sep-Oct;11(5):1119-1122. doi: 10.1016/j.brs.2018.06.006. Epub 2018 Jun 19.
BACKGROUND
Alpha (8-14 Hz) oscillatory power is linked to cortical excitability and corresponding modulations of sensory evoked potentials and perceptual detection performance. In somatosensory cortex (S1), negative linear and inverted U-shape relationships exist, whereas its effect on the primary motor cortex (M1) is hardly known.
OBJECTIVE
We used real-time EEG-triggered transcranial magnetic stimulation (TMS) of M1 to characterize the relationship between spontaneous sensorimotor mu-alpha power fluctuations at rest and corticospinal excitability.
METHODS
In 16 subjects, mu-alpha power was continuously monitored over the left sensorimotor cortex, and each 10%-percentile bin of the individual mu-alpha power distribution was repeatedly targeted in pseudorandomized order by single-pulse TMS of left M1, measuring motor evoked potentials (MEP) in the contralateral hand.
RESULTS
We found a weak positive relationship between mu-alpha power and MEP amplitude.
CONCLUSION
Sensorimotor mu-alpha power may reflect a net facilitation or disinhibition of M1, possibly resulting from mu-alpha based suppression of excitatory and inhibitory input from S1.
背景
α（8-14Hz）振荡功率与皮质兴奋性相关，可对应调节感觉诱发电位和感知检测性能。在体感皮层（S1）中，存在负线性和倒 U 形关系，但其对初级运动皮层（M1）的影响却鲜为人知。
目的
我们使用实时脑电图触发的经颅磁刺激（TMS）对 M1 进行刺激，以描述静息时自发性感觉运动μ-α功率波动与皮质脊髓兴奋性之间的关系。
方法
在 16 名受试者中，连续监测左侧感觉运动皮层的μ-α功率，并且以个体μ-α功率分布的 10%分位数为单位，通过对左侧 M1 的单次脉冲 TMS 进行重复随机靶向刺激，测量对侧手的运动诱发电位（MEP）。
结果
我们发现μ-α功率与 MEP 幅度之间存在微弱的正相关关系。
结论
感觉运动μ-α功率可能反映了 M1 的净易化或抑制，可能是由于μ-α 基于对来自 S1 的兴奋性和抑制性输入的抑制作用所致。
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