Department of Prosthodontics and Periodontics, Division of Periodontics - Piracicaba Dental School, State University of Campinas, Piracicaba, São Paulo, Brazil.
Clin Oral Investig. 2019 Feb;23(2):879-887. doi: 10.1007/s00784-018-2506-y. Epub 2018 Jun 12.
To evaluate the treatment of gingival recessions by semilunar coronally positioned flap plus enamel matrix derivative (SCPF + EMD).
Thirty patients with class I localized gingival recession were included. They were randomly allocated in two groups: SCPF + EMD and SCPF. Recession height (RH), recession width (RW), width of keratinized tissue (WKT), thickness of keratinized tissue (TKT), probing depth (PD), and clinical attachment level (CAL) were measured at baseline, 6 and 12 months post-surgery. Patient/professional evaluation of esthetics and root sensitivity was performed.
After 12 months, mean root coverage was 1.98 ± 0.33 mm for SCPF + EMD (90.86 ± 14.69%) and 1.85 ± 0.41 mm (79.76 ± 17.44%) for SCPF (p > 0.05). The esthetic evaluation by the patient showed preference for SCPF + EMD. According to the professional evaluation (QCE), the use of EMD decreases the appearance of postoperative scar tissue line. There was a significant reduction in root hypersensitivity with no further complaints by the patients.
The addition of EMD provides significantly better esthetics to SCPF, according to patient and professional assessments. SCPF + EMD is effective but not superior to SCPF for root coverage, after 12 months.
Previous clinical trials showed that the combination of EMD with coronally advanced flaps may enhance the outcome of root coverage. There is a lack of studies testing the combination of EMD with SCPF. The combination SCPF + EMD provides better esthetics when compared to the SCPF and is effective, but not superior, to SCPF for root coverage, after 12 months.
NCT02459704.
评估半月形冠向位瓣加釉基质衍生物（SCPF+EMD）治疗牙龈退缩的效果。
共纳入 30 例 I 类局限性牙龈退缩患者，随机分为 SCPF+EMD 组和 SCPF 组。分别于基线、术后 6 个月和 12 个月测量龈退缩高度（RH）、龈退缩宽度（RW）、角化龈宽度（WKT）、角化龈厚度（TKT）、探诊深度（PD）和临床附着水平（CAL）。并对美学和根面敏感进行患者/医生评估。
术后 12 个月，SCPF+EMD 组的平均根面覆盖率为 1.98±0.33mm（90.86%±14.69%），SCPF 组为 1.85±0.41mm（79.76%±17.44%）（p＞0.05）。患者评估倾向于 SCPF+EMD。根据专业评估（QCE），使用 EMD 可减少术后瘢痕组织线的外观。根面敏感显著减轻，患者无进一步抱怨。
根据患者和医生的评估，EMD 联合 SCPF 可显著改善美学效果。SCPF+EMD 在 12 个月时的根面覆盖率与 SCPF 相当，但效果并不优于 SCPF。
既往临床试验表明，EMD 联合冠向位瓣可增强根面覆盖的效果。目前尚无研究测试 EMD 联合 SCPF 的效果。与 SCPF 相比，SCPF+EMD 组合在美学效果上更优，在 12 个月时的根面覆盖率与 SCPF 相当，但效果并不优于 SCPF。
NCT02459704。
