观察到与斜向光刺激相关的瞬时光感受器运动。
observation of transient photoreceptor movement correlated with oblique light stimulation.
作者信息
Lu Yiming, Liu Changgeng, Yao Xincheng
机构信息
Department of Bioengineering, University of Illinois at Chicago, Chicago, IL 60607, USA.
Department of Ophthalmology and Visual Sciences, University of Illinois at Chicago, Chicago, IL 60612, USA.
出版信息
Proc SPIE Int Soc Opt Eng. 2018 Jan-Feb;10497. doi: 10.1117/12.2287262. Epub 2018 Feb 20.
Abstract
Rod-dominated transient retinal phototropism (TRP) has been observed in freshly isolated retinas, promising a noninvasive biomarker for high resolution assessment of retinal physiology. However, mapping of TRP is challenging due to its fast time course and sub-cellular signal magnitude. By developing a line-scanning and virtually structured detection based super-resolution ophthalmoscope, we report here observation of TRP in frog retina. characterization of TRP time course and magnitude were implemented by using variable light stimulus intensities.
摘要
在新鲜分离的视网膜中观察到杆状细胞主导的瞬态视网膜光向性（TRP），这有望成为一种用于视网膜生理学高分辨率评估的非侵入性生物标志物。然而，由于TRP的快速时间进程和亚细胞信号强度，对其进行映射具有挑战性。通过开发一种基于线扫描和虚拟结构检测的超分辨率检眼镜，我们在此报告了在青蛙视网膜中观察到TRP。通过使用可变光刺激强度来实现对TRP时间进程和强度的表征。
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