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肾上腺素在过敏反应治疗中的使用不足:错失的机会。

Underuse of epinephrine for the treatment of anaphylaxis: missed opportunities.

作者信息

Prince Benjamin T, Mikhail Irene, Stukus David R

机构信息

Division of Allergy and Immunology, Nationwide Children's Hospital, The Ohio State University College of Medicine, Columbus, OH, USA.

出版信息

J Asthma Allergy. 2018 Jun 20;11:143-151. doi: 10.2147/JAA.S159400. eCollection 2018.

Abstract

Epinephrine is the only effective treatment for anaphylaxis but studies routinely show underutilization. This is especially troubling given the fact that fatal anaphylaxis has been associated with delayed administration of epinephrine. Many potential barriers exist to the proper use of epinephrine during an anaphylactic reaction. This article will explore both patient-and physician-related factors, as well as misconceptions that all contribute to the underuse of epinephrine for the treatment of anaphylaxis.

摘要

肾上腺素是治疗过敏反应的唯一有效药物,但研究经常表明其使用不足。鉴于致命性过敏反应与肾上腺素给药延迟有关,这尤其令人担忧。在过敏反应期间,正确使用肾上腺素存在许多潜在障碍。本文将探讨与患者和医生相关的因素,以及导致肾上腺素在治疗过敏反应时使用不足的误解。

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本文引用的文献

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Are Expired EpiPens Still Viable?过期的肾上腺素自动注射器仍然可用吗?
J Allergy Clin Immunol Pract. 2017 Sep-Oct;5(5):1469-1470. doi: 10.1016/j.jaip.2017.06.026. Epub 2017 Sep 6.
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Do Corticosteroids Prevent Biphasic Anaphylaxis?皮质类固醇能否预防双相过敏反应?
J Allergy Clin Immunol Pract. 2017 Sep-Oct;5(5):1194-1205. doi: 10.1016/j.jaip.2017.05.022.
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The High Cost of Epinephrine Autoinjectors and Possible Alternatives.肾上腺素自动注射器的高昂成本及可能的替代方案
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Epinephrine for First-aid Management of Anaphylaxis.肾上腺素用于过敏反应的急救处理。
Pediatrics. 2017 Mar;139(3). doi: 10.1542/peds.2016-4006. Epub 2017 Feb 13.
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Food Allergy Trends and Epinephrine Autoinjector Presence in Summer Camps.夏令营中的食物过敏趋势与肾上腺素自动注射器配备情况
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