白藜芦醇研究的未来方向。
Future directions of resveratrol research.
作者信息
Wahl Devin, Bernier Michel, Simpson Stephen J, de Cabo Rafael, Le Couteur David G
机构信息
Charles Perkins Centre, University of Sydney, Sydney, Australia.
Aging and Alzheimer's Institute, ANZAC Research Institute, Concord Clinical School/Sydney Medical School, Concord, Australia.
出版信息
Nutr Healthy Aging. 2018 Jun 15;4(4):287-290. doi: 10.3233/NHA-170035.
Abstract
Resveratrol improves healthspan and lifespan in many organisms. Several different targets and mechanisms of action have been proposed to explain the beneficial effects of resveratrol on healthspan and longevity, including the activation of a family of proteins known as sirtuins and its action as a calorie restriction mimetic. In this mini-review, we discuss some of the most recent findings to date in the resveratrol field and suggest three areas of future research based on those results.
摘要
白藜芦醇可改善多种生物体的健康寿命和寿命。人们提出了几种不同的作用靶点和作用机制来解释白藜芦醇对健康寿命和长寿的有益影响，包括激活一类名为沉默调节蛋白的蛋白质家族以及其作为模拟热量限制的作用。在这篇小型综述中，我们讨论了白藜芦醇领域迄今为止的一些最新发现，并基于这些结果提出了三个未来研究领域。
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