University of Michigan, Ann Arbor, MI, USA.
University of Leuven, Leuven, Belgium.
World J Urol. 2018 Oct;36(10):1587-1592. doi: 10.1007/s00345-018-2388-2. Epub 2018 Jun 27.
Bowel function can be markedly changed after a spinal cord injury (SCI). These changes, and the care associated with managing the changes, can greatly impact a person's quality of life over a lifetime.
The purpose of the SIU-ICUD workgroup was to identify, assess, and summarize evidence and expert opinion-based themes and recommendations regarding bowel function and management in SCI populations.
As part of the SIU-ICUD joint consultation of Urologic Management of the Spinal Cord Injury, a workgroup was formed and comprehensive literature search of English language manuscripts regarding bowel physiology and management plans for the SCI patient. Articles were compiled, and recommendations in the chapter are based on group discussion and follow the Oxford Centre for Evidence-based Medicine system for levels of evidence (LOEs) and grades of recommendation (GORs).
Neurogenic bowel symptoms are highly prevalent in the SCI population. Patients with injuries above the conus medullaris have increased bowel motility and poor anorectal sphincter relaxation. Patients with injuries below the conus are more likely to have an areflexic colon and low sphincter tone. Conservative management strategies include diet modification and anorectal stimulation. There are few evidence-based pharmacologic interventions, which improve fecal transit time. Intestinal ostomy can be an effective treatment for reducing hours spent per week on bowel management and colostomy may be easier to manage than ileostomy due to solid vs liquid stool.
By understanding physiology and treatment options, patients and care teams can work together to achieve goals and maximize quality of life after injury.
脊髓损伤(SCI)后肠道功能可能会发生明显变化。这些变化以及与管理变化相关的护理会极大地影响一个人一生的生活质量。
SIU-ICUD 工作组的目的是确定、评估和总结有关 SCI 人群肠道功能和管理的证据和基于专家意见的主题和建议。
作为 SIU-ICUD 联合咨询“脊髓损伤的泌尿科管理”的一部分,成立了一个工作组,并对有关肠道生理学和 SCI 患者管理计划的英文文献进行了全面的文献检索。收集了文章,并根据小组讨论和遵循牛津循证医学中心(Oxford Centre for Evidence-based Medicine)的证据水平(Levels of Evidence,LOEs)和推荐等级(Grades of Recommendation,GORs)系统,为章节中的建议提供了依据。
神经源性肠道症状在 SCI 人群中非常普遍。圆锥以上损伤的患者肠道蠕动增加,肛门直肠括约肌松弛不良。圆锥以下损伤的患者更有可能出现反射性结肠和低括约肌张力。保守管理策略包括饮食调整和肛门直肠刺激。只有少数基于证据的药物干预措施可以改善粪便转运时间。肠道造口术可以作为减少每周用于肠道管理的时间的有效治疗方法,并且由于粪便为固体而非液体,结肠造口术可能比回肠造口术更容易管理。
通过了解生理学和治疗选择,患者和护理团队可以共同努力实现目标并在受伤后最大限度地提高生活质量。