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唇疱疹的发病机制：紫外线诱导损伤的实验研究

Pathogenesis of herpes simplex labialis: experimental induction of lesions with UV light.

作者信息

Spruance S L

出版信息

J Clin Microbiol. 1985 Sep;22(3):366-8. doi: 10.1128/jcm.22.3.366-368.1985.

DOI:10.1128/jcm.22.3.366-368.1985
PMID:2995436
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC268411/
Abstract

To develop a model system of herpes simplex labialis which would enable the study of patients before lesion onset, five patients were exposed to various doses of UV light from a sunlamp at their usual site of lesions. Six of 10 treatments resulted in the development of herpes labialis. Three of four treatments with the highest exposure levels led to large, vesicular, virus culture-positive sores. Side effects from sunlamp exposure were minimal.

摘要

为了开发一种唇疱疹模型系统，以便能够在病损发作前对患者进行研究，五名患者在其通常的病损部位接受了来自太阳灯的不同剂量紫外线照射。10次治疗中有6次导致唇疱疹发病。4次最高暴露水平的治疗中有3次导致出现大的水疱性、病毒培养阳性的溃疡。太阳灯照射的副作用极小。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3f6c/268411/8adc78dd6754/jcm00110-0065-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3f6c/268411/8adc78dd6754/jcm00110-0065-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3f6c/268411/8adc78dd6754/jcm00110-0065-a.jpg

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