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总睡眠时间与2型糖尿病风险:基于临床和流行病学研究的证据

Total Sleep Duration and Risk of Type 2 Diabetes: Evidence-Based On Clinical and Epidemiological Studies.

作者信息

Yadav Dhananjay, Cho Kyung-Hyun

机构信息

Department of Medical Biotechnology, Yeungnam University, Gyeongsan, 712-749, Korea.

出版信息

Curr Drug Metab. 2018;19(12):979-985. doi: 10.2174/1389200219666180628170431.

Abstract

BACKGROUND

Increasing incidences of type 2 diabetes make it necessary to have a better understanding of the risk factors for its prediction. Taking a note of resilience in risk factors, dynamics of the emerging factors other than traditional ones are showing a great interest in recent years which imprints a significant contribution in the occurrence of diabetes. Of different factors, sleep duration was acknowledged as a most common risk factor for diabetes.

METHODS

Adhering to the state of information available, studies recruited between 2010- 2016 a total of seven prospective studies including systematic review and meta-analysis were used to establish the relationship between sleep duration and type 2 diabetes. Studies were identified from Medline and Scopus. Studies included in this review was considered based on the different aspects such as maximum follow-up period, number of participants, including both sexes along with similar reference criteria of sleep duration.

RESULTS

With U-shaped association between sleep duration and the onset of diabetes, both short and long-term sleep duration was found contributing to the development of type 2 diabetes. Additionally, studies on the sex-related difference and pervasiveness of diabetes have also reported a profound relationship between short and long sleep hours and risk of developing type 2 diabetes.

CONCLUSION

Our study supports other studies on the relationship between total sleep duration and the risk of developing type 2 diabetes. This review emphasizes the importance of total sleep duration, sleep quality as a risk marker in monitoring type 2 diabetes.

摘要

背景

2型糖尿病发病率不断上升,因此有必要更好地了解其预测风险因素。鉴于风险因素中的复原力,近年来除传统因素外的新出现因素的动态变化引起了人们极大的兴趣,这些因素对糖尿病的发生有着重大影响。在不同因素中,睡眠时长被认为是糖尿病最常见的风险因素。

方法

根据现有信息状况,本研究纳入了2010年至2016年间开展的七项前瞻性研究,包括系统评价和荟萃分析,以确定睡眠时长与2型糖尿病之间的关系。研究通过Medline和Scopus进行检索。本综述纳入的研究是基于不同方面进行考量的,如最长随访期、参与者数量、性别涵盖情况以及睡眠时长的类似参考标准。

结果

睡眠时长与糖尿病发病呈U型关联,发现短期和长期睡眠时长均会促使2型糖尿病的发生。此外,关于糖尿病的性别差异和普遍性的研究也报告了短睡眠时长和长睡眠时长与2型糖尿病发病风险之间存在密切关系。

结论

我们的研究支持了其他关于总睡眠时长与2型糖尿病发病风险之间关系的研究。本综述强调了总睡眠时长、睡眠质量作为监测2型糖尿病风险标志物的重要性。

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