Redfield R R, Markham P D, Salahuddin S Z, Wright D C, Sarngadharan M G, Gallo R C
JAMA. 1985 Oct 18;254(15):2094-6.
Thirty-seven percent (15/41) of patients with human T-cell lymphotropic virus type III (HTLV-III) disease (acquired immunodeficiency syndrome [AIDS] or AIDS-related complex) sequentially evaluated at Walter Reed Army Medical Center, Washington, DC, acquired this infection from a partner(s) of the opposite sex. Demographic features of these 15 patients (ten males and five females) differed substantially from those for patients reported to the Centers for Disease Control. Heterosexual contact with partners who developed AIDS or who were at risk for AIDS was confirmed in six patients. The remaining nine patients had multiple (greater than 50) heterosexual partners and/or sexual contact with prostitutes. The method of sexual activity did not appear to be related to disease acquisition; however, this study clearly demonstrated that receptive anal intercourse was not a requirement. The observations reported herein provide further epidemiologic evidence to support the occurrence of bidirectional heterosexual transmission (both male to female and female to male) of HTLV-III infection and disease.
在华盛顿特区沃尔特·里德陆军医疗中心接受连续评估的人类嗜T淋巴细胞病毒III型（HTLV-III）疾病（获得性免疫缺陷综合征[艾滋病]或艾滋病相关综合征）患者中，37%（15/41）是从异性伴侣处感染此病的。这15名患者（10名男性和5名女性）的人口统计学特征与向疾病控制中心报告的患者有很大差异。6名患者被证实与患有艾滋病或有艾滋病风险的伴侣有异性接触。其余9名患者有多个（超过50个）异性伴侣和/或与妓女有性接触。性活动方式似乎与疾病感染无关；然而，本研究清楚地表明，接受性肛交并非必要条件。本文报告的观察结果提供了进一步的流行病学证据，支持HTLV-III感染和疾病双向异性传播（男性到女性和女性到男性）的发生。
