Department of Cardiology, Inselspital, Bern University Hospital, University of Bern, CH-3010 Bern, Switzerland.
Department of Cardiology, Inselspital, Bern University Hospital, University of Bern, CH-3010 Bern, Switzerland.
Int J Cardiol. 2018 Sep 15;267:133-138. doi: 10.1016/j.ijcard.2018.04.111.
Left ventricular hypertrophy (LVH) is a physiological adaptation to long-term endurance training. We investigated the impact of age at start of endurance training on LV geometry in a cohort of male, middle-aged, non-elite endurance athletes.
A total of 121 healthy, normotensive, Caucasian participants of a 10-mile race were recruited and assessed with an echocardiogram and a comprehensive interview. Athletes were classified based on patterns of LVH.
Thirty-five athletes (31%) had LVH. Athletes with eccentric LVH (16%) were significantly younger at start of endurance training compared to athletes with concentric LVH (15%, 14 ± 5 years vs. 31 ± 8 years; P < 0.001). Although the yearly volume of endurance training was comparable between athletes with eccentric and concentric LVH, athletes with eccentric LVH had shorter race times. All athletes with an increased LV end diastolic volume index (LVEDVI; ≥74 ml/m) started endurance training before or at age 25.
In our cohort of non-elite middle-aged runners, eccentric LVH was found only in athletes with an early start of endurance training. In case of a mature starting age, endurance training may, contrary to what is commonly assumed, also lead to concentric LVH. The consideration of endurance training starting age may lead to a better understanding of morphological adaptations of the heart.
左心室肥厚（LVH）是对长期耐力训练的生理适应。我们研究了耐力训练起始年龄对一群中年非精英耐力运动员的左心室几何结构的影响。
共招募了 121 名健康、血压正常的白种人参加 10 英里赛跑，并对他们进行了超声心动图和综合访谈评估。运动员根据 LVH 的模式进行分类。
35 名运动员（31%）存在 LVH。与具有向心性 LVH 的运动员（15%，14±5 岁）相比，具有离心性 LVH 的运动员（16%）开始耐力训练的年龄明显更年轻（31±8 岁；P<0.001）。尽管离心性和向心性 LVH 运动员的每年耐力训练量相当，但离心性 LVH 运动员的比赛用时更短。所有 LV 舒张末期容积指数（LVEDVI；≥74ml/m）增加的运动员均在 25 岁或之前开始耐力训练。
在我们的中年非精英跑步运动员队列中，仅在起始耐力训练年龄较早的运动员中发现了离心性 LVH。在成熟的起始年龄的情况下，耐力训练可能与普遍假设相反，也会导致向心性 LVH。考虑耐力训练起始年龄可能有助于更好地理解心脏的形态适应。
