Instituto de Óptica "Daza de Valdés", Consejo Superior de Investigaciones Científicas (CSIC), C/Serrano, 121, 28006, Madrid, Spain.
Fundación Jiménez Díaz, Madrid, Av. Reyes Católicos, 2, 28040, Madrid, Spain.
Sci Rep. 2018 Jun 29;8(1):9829. doi: 10.1038/s41598-018-28272-6.
In a cataract surgery, the opacified crystalline lens is replaced by an artificial intraocular lens (IOL). To optimize the visual quality after surgery, the intraocular lens to be implanted must be selected preoperatively for every individual patient. Different generations of formulas have been proposed for selecting the intraocular lens dioptric power as a function of its estimated postoperative position. However, very few formulas include crystalline lens information, in most cases only one-dimensional. The present study proposes a new formula to preoperatively estimate the postoperative IOL position (ELP) based on information of the 3-dimensional full shape of the crystalline lens, obtained from quantitative eye anterior segment optical coherence tomography imaging. Real patients were measured before and after cataract surgery (IOL implantation). The IOL position and the postoperative refraction estimation errors were calculated by subtracting the preoperative estimations from the actual values measured after surgery. The proposed ELP formula produced lower estimation errors for both parameters -ELP and refraction- than the predictions obtained with standard state-of-the-art methods, and opens new avenues to the development of new generation IOL power calculation formulas that improve refractive and visual outcomes.
在白内障手术中，混浊的晶状体被人工晶状体（IOL）取代。为了优化术后的视觉质量，必须为每位患者术前选择要植入的人工晶状体。已经提出了不同代的公式来选择作为其估计的术后位置的函数的人工晶状体屈光度。然而，很少有公式包括晶状体信息，在大多数情况下仅为一维。本研究提出了一种新的公式，根据定量眼前节光学相干断层扫描成像获得的晶状体的三维全形状信息，术前估计术后人工晶状体位置（ELP）。对白内障手术后的真实患者进行了测量（IOL 植入）。通过从手术后实际测量值中减去术前估计值来计算 IOL 位置和术后屈光估计误差。与使用标准最先进方法获得的预测值相比，所提出的 ELP 公式在这两个参数（ELP 和屈光）的估计误差更小，并为开发新一代改善屈光和视觉效果的人工晶状体屈光计算公式开辟了新途径。
