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主动脉根部置换的生物解决方案:保留瓣膜与生物人工血管。

Biological solutions to aortic root replacement: valve-sparing versus bioprosthetic conduit.

作者信息

De Paulis Ruggero, Scaffa Raffaele, Salica Andrea, Weltert Luca, Chirichilli Ilaria

机构信息

Department of Cardiac Surgery, European Hospital, Rome, Italy.

出版信息

J Vis Surg. 2018 May 9;4:94. doi: 10.21037/jovs.2018.04.12. eCollection 2018.

Abstract

Composite valve graft implantation described by Bentall and De Bono is a well-documented technique of aortic root replacement used for a large spectrum of pathologic conditions involving the aortic valve and the ascending aorta. While mechanical valves were initially used, biological prostheses were later introduced in order to avoid long-term anticoagulation and its related complications. The increasing age of patients who undergo aortic root surgery, and data supporting the use of a biological aortic valve in the younger population, have significantly increased the need for a composite biological valved conduit. However, parallel to the increased use of biological valve in the context of a Bentall operation, aortic valve-sparing (AVS) operation have also been performed in a growing number of patients. Sarsam and David described the remodeling and the reimplantation procedures more than 25 years ago with the aim of sparing otherwise normal aortic valves in the presence of a root aneurysm. Important achievements in this discipline have occurred over the past decade including development and refinement of valve preserving aortic root replacement techniques, development of a classification system for aortic insufficiency, surgical approaches to cusp disease with different cusp anatomy. Both procedures can now provide excellent root reconstruction and adequate clinical results in terms of late valve durability. The AVS technique offers several advantages over the Bentall procedure, such as no need for oral anticoagulation and lifestyle adjustments. AVS operations have become established alternatives to Bentall procedures for patients with aortic root pathology. However, data comparing the safety and durability of these approaches are lacking.

摘要

本塔尔(Bentall)和德博诺(De Bono)所描述的复合瓣膜移植术是一种有充分文献记载的主动脉根部置换技术,用于治疗涉及主动脉瓣和升主动脉的多种病理状况。最初使用的是机械瓣膜,后来引入了生物假体以避免长期抗凝及其相关并发症。接受主动脉根部手术的患者年龄不断增加,以及支持在年轻人群中使用生物主动脉瓣的数据,显著增加了对复合生物带瓣管道的需求。然而,在本塔尔手术中生物瓣膜使用增加的同时,越来越多的患者也接受了保留主动脉瓣(AVS)手术。25 多年前,萨尔萨姆(Sarsam)和大卫(David)描述了重塑和再植入手术,目的是在存在根部动脉瘤的情况下保留原本正常的主动脉瓣。在过去十年中,该领域取得了重要进展,包括保留瓣膜的主动脉根部置换技术的发展和完善、主动脉瓣关闭不全分类系统的开发、针对不同瓣叶解剖结构的瓣叶疾病的手术方法。就瓣膜晚期耐久性而言,这两种手术现在都能提供出色的根部重建和良好的临床效果。与本塔尔手术相比,AVS 技术具有几个优点,例如无需口服抗凝药和生活方式调整。对于患有主动脉根部疾病的患者,AVS 手术已成为本塔尔手术的既定替代方案。然而,缺乏比较这些方法安全性和耐久性的数据。

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