• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

血友病患者及其他长期接受血液制品替代治疗患者中人类嗜T淋巴细胞病毒III型(HTLV-III)抗体的流行情况。

Prevalence of antibodies to human T-lymphotropic virus-III (HTLV-III) in hemophiliacs and other patients chronically substituted with blood products.

作者信息

Erfle V, Hehlmann R, Mellert W, Goebel F D, Rasokat H, Lechler E, Hellstern P, Köhler M, Seifried E, Heimpel H

出版信息

Blut. 1985 Oct;51(4):243-9. doi: 10.1007/BF00320518.

DOI:10.1007/BF00320518
PMID:2996664
Abstract

The prevalence of antibodies to human T-lymphotropic virus III (HTLV-III) was determined in a total of 140 hemophiliacs and 36 polytransfused patients from three medical centers by an enzyme linked immunosorbent assay (ELISA) and confirmatory tests. 58 hemophiliacs (41.4%) were seropositive. In all instances where the origin of the coagulation factors given to these patients could be determined, blood products came from the United States. In addition, 2 of 36 polytransfused patients, mostly with acute leukemias, who were transfused with blood products from local donors were positive for HTLV-III antibodies. No HTLV-III antibodies were detected in 237 blood donors selected in part from the donor pool of the polytransfused patients.

摘要

通过酶联免疫吸附测定法(ELISA)和确证试验,对来自三个医疗中心的140名血友病患者和36名多次输血患者进行了人类嗜T淋巴细胞病毒III型(HTLV-III)抗体的流行率测定。58名血友病患者(41.4%)血清呈阳性。在所有能够确定给予这些患者的凝血因子来源的情况下,血液制品均来自美国。此外,36名多次输血患者中有2名主要患有急性白血病,他们接受了来自当地献血者的血液制品,其HTLV-III抗体呈阳性。在部分从多次输血患者的献血者库中挑选出的237名献血者中未检测到HTLV-III抗体。

相似文献

1
Prevalence of antibodies to human T-lymphotropic virus-III (HTLV-III) in hemophiliacs and other patients chronically substituted with blood products.血友病患者及其他长期接受血液制品替代治疗患者中人类嗜T淋巴细胞病毒III型(HTLV-III)抗体的流行情况。
Blut. 1985 Oct;51(4):243-9. doi: 10.1007/BF00320518.
2
HTLV III antibodies and immunological alterations in hemophilia patients.血友病患者中的人类嗜T淋巴细胞病毒III型抗体及免疫改变
Klin Wochenschr. 1986 Feb 3;64(3):115-24. doi: 10.1007/BF01732634.
3
Prevalence of antibodies to HTLV-III in AIDS risk groups in West Germany.
Cancer Res. 1985 Sep;45(9 Suppl):4627s-4629s.
4
Detection of antibodies to human T-lymphotropic viruses type I and III in Japanese hemophiliacs.
AIDS Res. 1983;1(5):353-8. doi: 10.1089/aid.1.1983.1.353.
5
Antibody to human T-lymphotropic virus type III in wives of hemophiliacs. Evidence for heterosexual transmission.血友病患者妻子中人类嗜T淋巴细胞病毒III型抗体。异性传播的证据。
Ann Intern Med. 1985 May;102(5):623-6. doi: 10.7326/0003-4819-102-5-623.
6
Human T-lymphotropic retrovirus type III/lymphadenopathy-associated virus antibody. Association with hemophiliacs' immune status and blood component usage.
JAMA. 1985 Jun 21;253(23):3409-15.
7
Radioimmunoassay and enzyme-linked immunoassay of antibodies to the core protein (P24) of human T-lymphotropic virus (HTLV III).人嗜T淋巴细胞病毒(HTLV III)核心蛋白(P24)抗体的放射免疫测定及酶联免疫测定
J Virol Methods. 1985 May;11(1):75-86. doi: 10.1016/0166-0934(85)90126-0.
8
HTLV-III/LAV antibody status of spouses and household contacts assisting in home infusion of hemophilia patients.
Blood. 1985 Sep;66(3):703-5.
9
Detection of acquired immunodeficiency syndrome (AIDS) retrovirus antibody by lymphadenopathy-associated virus (LAV) enzyme immunoassay in low- and high-risk populations.通过淋巴结病相关病毒(LAV)酶免疫测定法在低风险和高风险人群中检测获得性免疫缺陷综合征(AIDS)逆转录病毒抗体。
Transfusion. 1986 May-Jun;26(3):299-301. doi: 10.1046/j.1537-2995.1986.26386209394.x.
10
Prevalence of antibodies to AIDS-associated retrovirus in in- and out-patients in Japan.日本门诊和住院患者中艾滋病相关逆转录病毒抗体的流行情况。
AIDS Res. 1986 Dec;2 Suppl 1:S29-34.

引用本文的文献

1
HTLV III antibodies and immunological alterations in hemophilia patients.血友病患者中的人类嗜T淋巴细胞病毒III型抗体及免疫改变
Klin Wochenschr. 1986 Feb 3;64(3):115-24. doi: 10.1007/BF01732634.
2
Seroepidemiology of HTLV-III (LAV) in the Federal Republic of Germany.德意志联邦共和国HTLV-III(LAV)的血清流行病学研究。
Klin Wochenschr. 1985 Mar 1;63(5):233-5. doi: 10.1007/BF01731176.

本文引用的文献

1
Acquired immunodeficiency syndrome (AIDS) associated with transfusions.与输血相关的获得性免疫缺陷综合征(艾滋病)。
N Engl J Med. 1984 Jan 12;310(2):69-75. doi: 10.1056/NEJM198401123100201.
2
Update: acquired immunodeficiency syndrome (AIDS) in persons with hemophilia.最新消息:血友病患者中的获得性免疫缺陷综合征(艾滋病)
MMWR Morb Mortal Wkly Rep. 1984 Oct 26;33(42):589-91.
3
Antibodies to a retrovirus etiologically associated with acquired immunodeficiency syndrome (AIDS) in populations with increased incidences of the syndrome.
MMWR Morb Mortal Wkly Rep. 1984 Jul 13;33(27):377-9.
4
Selective tropism of lymphadenopathy associated virus (LAV) for helper-inducer T lymphocytes.淋巴结病相关病毒(LAV)对辅助诱导性T淋巴细胞的选择性嗜性。
Science. 1984 Jul 6;225(4657):59-63. doi: 10.1126/science.6328660.
5
Antibodies reactive with human T-lymphotropic retroviruses (HTLV-III) in the serum of patients with AIDS.艾滋病患者血清中与人类嗜T淋巴细胞逆转录病毒(HTLV - III)反应的抗体。
Science. 1984 May 4;224(4648):506-8. doi: 10.1126/science.6324345.
6
ELISA for the detection and quantification of C-type viral glycoprotein (gp70) using antibodies that recognize the protein moieties of the glycoproteins.使用识别糖蛋白蛋白质部分的抗体,通过酶联免疫吸附测定法检测和定量C型病毒糖蛋白(gp70)。
J Virol Methods. 1981 Jun;2(6):357-66. doi: 10.1016/0166-0934(81)90059-8.
7
Frequent detection and isolation of cytopathic retroviruses (HTLV-III) from patients with AIDS and at risk for AIDS.从艾滋病患者和有患艾滋病风险的人群中频繁检测和分离出细胞病变逆转录病毒(HTLV-III)。
Science. 1984 May 4;224(4648):500-3. doi: 10.1126/science.6200936.
8
Methods in laboratory investigation. Application of the indirect enzyme-linked immunosorbent assay microtest to the detection and surveillance of human t cell leukemia-lymphoma virus.实验室研究方法。间接酶联免疫吸附试验微量检测在人类T细胞白血病-淋巴瘤病毒检测与监测中的应用。
Lab Invest. 1983 Sep;49(3):371-7.
9
Isolation of a T-lymphotropic retrovirus from a patient at risk for acquired immune deficiency syndrome (AIDS).从一名有获得性免疫缺陷综合征(艾滋病)风险的患者体内分离出一种嗜T淋巴细胞逆转录病毒。
Science. 1983 May 20;220(4599):868-71. doi: 10.1126/science.6189183.
10
HTLV-III antibody frequency and severity of lymphadenopathy.
Lancet. 1984 Dec 8;2(8415):1347. doi: 10.1016/s0140-6736(84)90862-6.