Therrien Amanda S, Bastian Amy J
Center for Movement Studies, Kennedy Krieger Institute, USA; Department of Neuroscience, Johns Hopkins School of Medicine, Baltimore, MD, USA.
Center for Movement Studies, Kennedy Krieger Institute, USA; Department of Neuroscience, Johns Hopkins School of Medicine, Baltimore, MD, USA.
Neurosci Lett. 2019 Jan 1;688:37-40. doi: 10.1016/j.neulet.2018.06.055. Epub 2018 Jun 30.
In this article, we review a broad range of studies of cerebellar function and dysfunction and interpret them within the framework that the cerebellum acts as part of a mechanism of predictive control. We describe studies that span human behaviour and consider the motor and sensory impairments that result from cerebellar damage. We conclude that a parsimonious explanation of cerebellar function is as a predictor of the sensory outcomes of movement. However, future studies are needed to more rigorously test this hypothesis and determine how the cerebellar circuit might perform this type of computation.
在本文中,我们回顾了一系列关于小脑功能与功能障碍的研究,并在小脑作为预测控制机制一部分的框架内对其进行解读。我们描述了涵盖人类行为的研究,并考量了小脑损伤导致的运动和感觉障碍。我们得出结论,对小脑功能的一种简洁解释是它作为运动感觉结果的预测器。然而,未来需要进行更严格的研究来检验这一假设,并确定小脑回路如何执行这类计算。