在所有人类染色体着丝粒处发现的α卫星重复DNA家族的一个克隆序列p82H。
A cloned sequence, p82H, of the alphoid repeated DNA family found at the centromeres of all human chromosomes.
作者信息
Mitchell A R, Gosden J R, Miller D A
出版信息
Chromosoma. 1985;92(5):369-77. doi: 10.1007/BF00327469.
PMID:2996845
Abstract
Clone p82H is a human DNA sequence which hybridises in situ exclusively to the centromeric regions of all human chromosomes. It is composed of approximately 14 tandemly repeated variants of a basic 172 bp sequence, and is related to the alphoid family. The organisation of the family of cross-hybridising sequences, detected by the clone p82H, is described both in the human genome and on certain chromosomes, and its relationship to known sequence families is discussed.
摘要
克隆体p82H是一段人类DNA序列，它在原位杂交时仅与所有人类染色体的着丝粒区域杂交。它由一个基本的172 bp序列的大约14个串联重复变体组成，并且与α卫星家族相关。描述了由克隆体p82H检测到的交叉杂交序列家族在人类基因组和某些染色体上的组织情况，并讨论了它与已知序列家族的关系。
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