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前庭康复治疗后难治性头晕患者认知功能的变化。

Changes in cognitive function in patients with intractable dizziness following vestibular rehabilitation.

机构信息

Unit of Public Health and Preventive Medicine, School of Medicine, Yokohama City University, Yokohama, Japan.

Department of Otolaryngology, National Hospital Organization Tokyo Medical Center, Tokyo, Japan.

出版信息

Sci Rep. 2018 Jul 3;8(1):9984. doi: 10.1038/s41598-018-28350-9.

Abstract

The purpose of the present study was to investigate changes in cognitive functions, including visuospatial ability, attention, and executive function in patients with intractable dizziness following vestibular rehabilitation. The correlations between improvements in cognitive function and dizziness-related variables and emotional distress were also explored. During hospitalization for 5 days, participants were trained on a vestibular rehabilitation program. Participants completed questionnaires including the Dizziness Handicap Inventory (DHI), Hospital Anxiety and Depression Scale (HADS), and Trail Making Test (TMT), which were used to assess cognitive function. The center of gravity fluctuation measurement and timed up and go test (TUG), which were objective dizziness severity indexes, were performed before, 1 month after, and 4 months after hospitalization. Following vestibular rehabilitation, participants exhibited a significant improvement in the TMT, DHI, HADS, and TUG scores. Correlation analysis between the variables at each time point indicated that TMT scores positively correlated with TUG at baseline. The correlation between changes observed in the TUG and TMT scores was not significant. The degree of improvement of the TUG score did not bear a linear relationship with that of the TMT scores. However, these correlation results were not completely consistent with those in the multiply imputed dataset.

摘要

本研究旨在探讨前庭康复治疗后难治性头晕患者认知功能(包括视空间能力、注意力和执行功能)的变化,并探讨认知功能改善与头晕相关变量和情绪困扰之间的相关性。患者住院 5 天,接受前庭康复训练。患者完成了问卷调查,包括头晕残障程度评估量表(DHI)、医院焦虑抑郁量表(HADS)和连线测试(TMT),用于评估认知功能。在住院前、出院后 1 个月和 4 个月时,还进行了重心波动测量和计时起身行走测试(TUG),这是客观评估头晕严重程度的指标。经过前庭康复治疗,患者的 TMT、DHI、HADS 和 TUG 评分均显著提高。各时间点变量之间的相关性分析表明,TMT 评分与基线时的 TUG 呈正相关。TUG 和 TMT 评分变化之间的相关性不显著。TUG 评分改善的程度与 TMT 评分的改善程度没有线性关系。然而,这些相关性结果与多重插补数据集不完全一致。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ebc8/6030069/63203e18c417/41598_2018_28350_Fig1_HTML.jpg

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