Geriatric Department, University Hospitals of Strasbourg, Strasbourg, France.
Faculty of Medicine, Research Laboratory Mitochondria, Oxidative Stress and Muscle Resistance (MSP, EA-3072), Department of Physiology, Strasbourg University, Strasbourg, France.
Scand J Med Sci Sports. 2018 Nov;28(11):2284-2292. doi: 10.1111/sms.13257. Epub 2018 Jul 22.
Interval aerobic training programs (IATP) improve cardiorespiratory and endurance parameters. They are, however, unsuitable to seniors as frequently associated with occurrence of exhaustion and muscle pain. The purpose of this study was to measure the benefits of an IATP designed with recovery bouts (IATP-R) in terms of cardiorespiratory and endurance parameters and its acceptability among seniors (≥70 years). Sedentary healthy volunteers were randomly assigned either to IATP-R or sedentary lifestyle. All participants performed an incremental cycle exercise and 6-minute walk test (6-MWT) at baseline and 9.5 weeks later. The first ventilatory threshold (VT ); maximal tolerated power (MTP); peak of oxygen uptake (VO ); maximal heart rate (HR ); and distance walked at 6-MWT were thus measured. IATP-R consisted of 19 sessions of 30-minute (6 × 4-min at VT + 1-minute at 40% of VT ) cycling exercise over 9.5 weeks. With an adherence rate of 94.7% without any significant adverse events, 9.5 weeks of IATP-R, compared to controls, enhanced endurance (VT : +18.3 vs -4.6%; HR at baseline VT : -5.9 vs +0.2%) and cardiorespiratory parameters (VO : +14.1 vs -2.7%; HR : +1.6 vs -1.7%; MTP: +19.2 vs -2.3%). The walk distance at the 6-MWT was also significantly lengthened (+11.6 vs. -3.1%). While these findings resulted from an interim analysis planned when 30 volunteers were enrolled in both groups, IATP-R appeared as effective, safe, and applicable among sedentary healthy seniors. These characteristics are decisive for exercise training prescription and adherence.
间歇有氧运动训练计划（IATP）可改善心肺和耐力参数。然而，它们不适合老年人，因为它们经常与疲劳和肌肉疼痛有关。本研究的目的是测量设计有恢复期的 IATP（IATP-R）在心肺和耐力参数方面的益处，以及其在老年人（≥70 岁）中的可接受性。久坐的健康志愿者被随机分配到 IATP-R 或久坐的生活方式组。所有参与者在基线和 9.5 周后都进行了递增式自行车运动和 6 分钟步行测试（6-MWT）。因此，测量了第一通气阈（VT）；最大耐受功率（MTP）；峰值摄氧量（VO ）；最大心率（HR）；以及 6-MWT 步行距离。IATP-R 由 9.5 周内 19 次 30 分钟（6×4 分钟在 VT 处+1 分钟在 VT 的 40%处）自行车运动组成。由于依从率为 94.7%，没有任何重大不良事件，与对照组相比，9.5 周的 IATP-R 增强了耐力（VT：+18.3% vs -4.6%；VT 时的 HR 基线：-5.9% vs +0.2%）和心肺参数（VO：+14.1% vs -2.7%；HR：+1.6% vs -1.7%；MTP：+19.2% vs -2.3%）。6-MWT 的步行距离也明显延长（+11.6% vs -3.1%）。虽然这些发现是在两组各有 30 名志愿者入组时进行的中期分析计划的结果，但 IATP-R 似乎对久坐的健康老年人有效、安全且适用。这些特征对于运动训练处方和依从性具有决定性意义。
