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生育激素的自我监测:自然计划生育的新时代?

Self-Monitoring of Fertility Hormones: A New Era for Natural Family Planning?

作者信息

Blackwell Leonard, Cooke Delwyn, Brown Simon

机构信息

Massey University, Palmerston North, Manawatu, New Zealand.

Science Haven Limited, Palmerston North, Manawatu, New Zealand.

出版信息

Linacre Q. 2018 Feb;85(1):26-34. doi: 10.1177/0024363918756387. Epub 2018 Mar 28.

Abstract

Natural family planning (NFP) methods have served many generations well, and in particular, the symptothermal or symptohormonal methods. The comparison of daily mucus and temperature records for individual cycles with daily hormone measurements, which is now possible, shows that some of the assumptions underlying NFP may not be completely accurate. The various methods are inadvertently depending on an element of chance, which, of course, cannot be known by the NFP user. However, it is statistically inevitable that such errors will result eventually in an unexpected pregnancy, and these discrepancies are the likely reason for the method failures. Further research and integration of home hormone measurements with NFP symptoms are needed. Traditional NFP methods, based on the observations of temperature, mucus, and luteinizing hormone, can work well. However, these data are sometimes difficult to interpret, and significant changes in the variables are sometimes "missing" from some cycles. Changes in these variables are elicited by the estrogen and progesterone released from the ovaries. It follows that the direct measures of events in the ovaries are the levels of estrogen and progesterone or their derivatives in blood or urine. Measurements of urinary derivatives of estrogen and progesterone can be used to monitor the ovaries directly and are clearer indicators than traditional NFP methods.

摘要

自然计划生育(NFP)方法已经很好地服务了几代人,尤其是症状体温法或症状激素法。现在可以将个体周期的每日黏液和体温记录与每日激素测量结果进行比较,结果表明,NFP所依据的一些假设可能并不完全准确。各种方法在不经意间都依赖于一定的偶然性因素,当然,NFP使用者并不知道这些因素。然而,从统计学角度来看,这些误差最终不可避免地会导致意外怀孕,而这些差异很可能是方法失败的原因。需要进一步研究并将家庭激素测量与NFP症状相结合。基于体温、黏液和促黄体生成素观察的传统NFP方法可能会有效。然而,这些数据有时难以解读,而且某些周期中变量的显著变化有时会“缺失”。这些变量的变化是由卵巢释放的雌激素和孕激素引起的。因此,卵巢内事件的直接测量指标是血液或尿液中雌激素和孕激素或其衍生物的水平。雌激素和孕激素的尿衍生物测量可用于直接监测卵巢,并且比传统NFP方法更明确。

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Natural methods of family planning.计划生育的自然方法。
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