• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

巴西活产儿中与寨卡病毒感染相关的先天性综合征:2015 - 2016年报告及确诊病例分布描述

Congenital syndrome associated with Zika virus infection among live births in Brazil: a description of the distribution of reported and confirmed cases in 2015-2016.

作者信息

França Giovanny Vinícius Araújo de, Pedi Vaneide Daciane, Garcia Márcio Henrique de Oliveira, Carmo Greice Madeleine Ikeda do, Leal Mariana Bertol, Garcia Leila Posenato

机构信息

Ministério da Saúde, Secretaria de Vigilância em Saúde, Brasília, DF, Brasil.

Ministério da Saúde, Secretaria de Atenção à Saúde, Brasília, DF, Brasil.

出版信息

Epidemiol Serv Saude. 2018 Jul 2;27(2):e2017473. doi: 10.5123/S1679-49742018000200014.

DOI:10.5123/S1679-49742018000200014
PMID:29972474
Abstract

OBJECTIVE

to describe the temporal and spatial distribution of reported and confirmed cases of congenital Zika virus syndrome (CZS) in live births in Brazil during 2015-2016.

METHODS

we conducted a descriptive study with data from the Public Health Events Registry, including cases born in 2015 or 2016, and registered between epidemiological week 45/2015 and 2/2017.

RESULTS

we analyzed 9.953 reported cases, of which 2.018 (20.3%) were confirmed and 2.819 (28.3%) were still under investigation at the epidemiological week 2/2017; 404 (4.1%) out of the 9.953 cases had laboratory confirmation for Zika virus; the prevalence of confirmed cases of CZS was 3.8/10 thousand livebirths in 2015 and 3.1/10 thousand live births in 2016.

CONCLUSION

one fifth of the cases reported in 2015-16 were confirmed the CZS, reinforcing their relevance as a public health problem; efforts aimed at the diagnostic confirmation of the syndrome should be prioritized.

摘要

目的

描述2015 - 2016年巴西活产儿中先天性寨卡病毒综合征(CZS)报告病例和确诊病例的时空分布情况。

方法

我们利用公共卫生事件登记处的数据进行了一项描述性研究,数据包括2015年或2016年出生且在2015年第45周和2017年第2周之间登记的病例。

结果

我们分析了9953例报告病例,其中2018例(20.3%)得到确诊,在2017年第2周时仍有2819例(28.3%)正在调查中;9953例病例中有404例(4.1%)经实验室确诊感染寨卡病毒;2015年CZS确诊病例的患病率为每10000例活产儿中有3.8例,2016年为每10000例活产儿中有3.1例。

结论

2015 - 2016年报告病例中有五分之一被确诊为CZS,这凸显了其作为公共卫生问题的重要性;应优先努力对该综合征进行诊断确认。

相似文献

1
Congenital syndrome associated with Zika virus infection among live births in Brazil: a description of the distribution of reported and confirmed cases in 2015-2016.巴西活产儿中与寨卡病毒感染相关的先天性综合征:2015 - 2016年报告及确诊病例分布描述
Epidemiol Serv Saude. 2018 Jul 2;27(2):e2017473. doi: 10.5123/S1679-49742018000200014.
2
Descriptive report of cases of congenital syndrome associated with Zika virus infection in the state of São Paulo, Brazil, from 2015 to 2017.2015年至2017年巴西圣保罗州与寨卡病毒感染相关的先天性综合征病例描述报告。
Epidemiol Serv Saude. 2018 Oct 22;27(3):e2017382. doi: 10.5123/S1679-49742018000300012.
3
Microcephaly in Piauí, Brazil: descriptive study during the Zika virus epidemic, 2015-2016.巴西皮奥伊州的小头畸形:2015 - 2016年寨卡病毒流行期间的描述性研究
Epidemiol Serv Saude. 2018 Feb 1;27(1):e20163692. doi: 10.5123/S1679-49742018000100002.
4
Congenital Zika virus syndrome in Brazil: a case series of the first 1501 livebirths with complete investigation.巴西先天性寨卡病毒综合征:1501 例首例活产儿完整调查的病例系列。
Lancet. 2016 Aug 27;388(10047):891-7. doi: 10.1016/S0140-6736(16)30902-3. Epub 2016 Jun 29.
5
Infection-related microcephaly after the 2015 and 2016 Zika virus outbreaks in Brazil: a surveillance-based analysis.巴西 2015 年和 2016 年寨卡病毒疫情后的感染相关小头畸形:基于监测的分析。
Lancet. 2017 Aug 26;390(10097):861-870. doi: 10.1016/S0140-6736(17)31368-5. Epub 2017 Jun 21.
6
Prevalence and causes of congenital microcephaly in the absence of a Zika virus outbreak in southern Brazil.巴西南部无寨卡病毒疫情时先天性小头畸形的流行情况及病因。
J Pediatr (Rio J). 2019 Sep-Oct;95(5):600-606. doi: 10.1016/j.jped.2018.05.013. Epub 2018 Jul 4.
7
Descriptive study of suspected congenital Zika syndrome cases during the 2015-2016 epidemic in Brazil.对2015 - 2016年巴西疫情期间疑似先天性寨卡综合征病例的描述性研究。
Rev Soc Bras Med Trop. 2019 Jul 18;52:e20190105. doi: 10.1590/0037-8682-0105-2019.
8
Health and Development at Age 19-24 Months of 19 Children Who Were Born with Microcephaly and Laboratory Evidence of Congenital Zika Virus Infection During the 2015 Zika Virus Outbreak - Brazil, 2017.2017年巴西,19名在2015年寨卡病毒疫情期间出生时患有小头畸形且有先天性寨卡病毒感染实验室证据的儿童在19至24个月大时的健康与发育情况。
MMWR Morb Mortal Wkly Rep. 2017 Dec 15;66(49):1347-1351. doi: 10.15585/mmwr.mm6649a2.
9
Clinical-epidemiological description of live births with microcephaly in the state of Sergipe, Brazil, 2015.2015年巴西塞尔希培州小头畸形活产儿的临床流行病学描述
Epidemiol Serv Saude. 2017 Apr-Jun;26(2):245-254. doi: 10.5123/S1679-49742017000200002.
10
Socioeconomic disparities associated with symptomatic Zika virus infections in pregnancy and congenital microcephaly: A spatiotemporal analysis from Goiânia, Brazil (2016 to 2020).与妊娠和先天性小头畸形相关的症状性寨卡病毒感染的社会经济差异:巴西戈亚尼亚的时空分析(2016 年至 2020 年)。
PLoS Negl Trop Dis. 2022 Jun 17;16(6):e0010457. doi: 10.1371/journal.pntd.0010457. eCollection 2022 Jun.

引用本文的文献

1
Investigating the association between yellow fever vaccination and symptomatic acute Zika virus infection: a case-control study.调查黄热病疫苗接种与有症状的急性寨卡病毒感染之间的关联:一项病例对照研究。
Rev Soc Bras Med Trop. 2025 Jun 2;58:e004042025. doi: 10.1590/0037-8682-0233-2024. eCollection 2025.
2
An immunocompetent mouse model revealed that congenital Zika virus infection disrupted hippocampal function by activating autophagy.一个具有免疫活性的小鼠模型显示,先天性寨卡病毒感染通过激活自噬破坏了海马体功能。
Emerg Microbes Infect. 2025 Dec;14(1):2465327. doi: 10.1080/22221751.2025.2465327. Epub 2025 Feb 28.
3
Sociodemographic and Clinical Factors for Microcephaly Secondary to Teratogenic Infections in Brazil: An Ecological Study.
巴西因致畸性感染导致小头畸形的社会人口学和临床因素:一项生态学研究。
Viruses. 2023 Jul 31;15(8):1675. doi: 10.3390/v15081675.
4
Disease burden of congenital Zika virus syndrome in Brazil and its association with socioeconomic data.巴西先天性寨卡病毒综合征的疾病负担及其与社会经济数据的关联。
Sci Rep. 2023 Jul 23;13(1):11882. doi: 10.1038/s41598-023-38553-4.
5
The Anti-Dengue Virus Peptide DV2 Inhibits Zika Virus Both In Vitro and In Vivo.抗登革热病毒肽 DV2 在体外和体内均能抑制寨卡病毒。
Viruses. 2023 Mar 25;15(4):839. doi: 10.3390/v15040839.
6
Congenital anomalies during the 2015-2018 Zika virus epidemic: a population-based cross-sectional study.2015-2018 年寨卡病毒流行期间的先天性异常:一项基于人群的横断面研究。
BMC Public Health. 2022 Nov 12;22(1):2069. doi: 10.1186/s12889-022-14490-1.
7
My child is growing and now? Exploring the environmental needs of children with congenital Zika syndrome according to their caregivers' perceptions.我的孩子在成长,现在呢?根据照顾者的认知,探索先天性寨卡综合征儿童的环境需求。
Health Expect. 2022 Dec;25(6):2828-2836. doi: 10.1111/hex.13587. Epub 2022 Oct 25.
8
Population-based surveillance for congenital zika virus syndrome: a latent class analysis of recorded cases from 2015-2018.基于人群的先天性寨卡病毒综合征监测:2015-2018 年记录病例的潜在类别分析。
BMC Pregnancy Childbirth. 2022 Jun 29;22(1):530. doi: 10.1186/s12884-022-04860-3.
9
Congenital Zika syndrome and living conditions in the largest city of northeastern Brazil.先天性寨卡综合征与巴西东北部最大城市的生活条件
BMC Public Health. 2022 Jun 20;22(1):1231. doi: 10.1186/s12889-022-13614-x.
10
Assessment of the feasibility of Juntos: A support programme for families of children affected by Congenital Zika Syndrome.评估“携手共进”项目的可行性:一项针对受先天性寨卡综合征影响儿童家庭的支持计划。
Wellcome Open Res. 2022 Mar 4;7:77. doi: 10.12688/wellcomeopenres.17419.1. eCollection 2022.