Rzepka-Wrona Patrycja, Skoczynski Szymon, Wrona Dawid, Barczyk Adam
Department of Pneumonology, School of Medicine in Katowice, Medical University of Silesia, Katowice, Poland.
Department of Organic Chemistry, Bioorganic Chemistry and Biotechnology, Faculty of Chemistry, Silesian University of Technology, Gliwice, Poland.
Can Respir J. 2018 Jun 3;2018:8959370. doi: 10.1155/2018/8959370. eCollection 2018.
The administration of aerosolized medication is a basic therapy for patients with numerous respiratory tract diseases, including obstructive airway diseases (OADs), cystic fibrosis (CF), and infectious airway diseases. The management and care for patients requiring mechanical ventilation remains one of the greatest challenges for medical practitioners, both in intensive care units (ICUs) and pulmonology wards. Aerosol therapy is often necessary for patients receiving noninvasive ventilation (NIV), which may be stopped for the time of drug delivery and administered through a metered-dose inhaler or nebulizer in the traditional way. However, in most severe cases, this may result in rapid deterioration of the patient's clinical condition. Unfortunately, only limited number of original well-planned studies addressed this problem. Due to inconsistent information coming from small studies, there is a need for more precise data coming from large prospective real life studies on inhalation techniques in patients receiving NIV.
雾化药物给药是众多呼吸道疾病患者的基本治疗方法，这些疾病包括阻塞性气道疾病（OADs）、囊性纤维化（CF）和感染性气道疾病。对于需要机械通气的患者，无论是在重症监护病房（ICU）还是肺病病房，其管理和护理仍然是医学从业者面临的最大挑战之一。接受无创通气（NIV）的患者通常需要进行雾化治疗，在给药时可能需要停止无创通气，并通过传统的定量吸入器或雾化器进行给药。然而，在大多数严重情况下，这可能会导致患者临床状况迅速恶化。不幸的是，只有少数精心设计的原始研究涉及了这个问题。由于小型研究提供的信息不一致，因此需要来自大型前瞻性实际研究的更精确数据，以了解接受无创通气患者的吸入技术。
