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重楼替代资源的不懈研究

Untiring Researches for Alternative Resources of Rhizoma Paridis.

作者信息

Qin Xu-Jie, Ni Wei, Chen Chang-Xiang, Liu Hai-Yang

机构信息

State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, and Yunnan Key Laboratory of Medicinal Chemistry, Kunming, 650201, People's Republic of China.

出版信息

Nat Prod Bioprospect. 2018 Aug;8(4):265-278. doi: 10.1007/s13659-018-0179-5. Epub 2018 Jul 4.

Abstract

Rhizoma Paridis (RP, ), a traditional Chinese medicine, is the rhizoma of Paris polyphylla var. yunnanensis (PPY) or P. polyphylla var. chinensis which are widely used as important raw materials for several Chinese patent drugs. However, the wild resources of these herbs have become less and less due to their slow-growing characteristics and previously excessive excavation. This review covers untiring investigations on alternative resources of RP by our research group over the past decades, including non-medicinal parts of PPY as well as other plants of Liliaceae and Liliflorae families. The arial parts of PPY and the whole plants of Trillium kamtschaticum might be alternative resources for RP based on the fact that they shared the same or similar saponins and bioactivities.

摘要

重楼是一种传统中药,为云南重楼或华重楼的根茎,它们被广泛用作多种中成药的重要原料。然而,由于这些草药生长缓慢且此前过度采挖,其野生资源已越来越少。本综述涵盖了我们研究小组在过去几十年中对重楼替代资源的不懈研究,包括云南重楼的非药用部位以及百合科和百合亚科的其他植物。基于云南重楼的地上部分和东北延龄草的全草含有相同或相似的皂苷及生物活性这一事实,它们可能是重楼的替代资源。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f4ed/6102180/3ec98e4d103a/13659_2018_179_Fig1_HTML.jpg

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