• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

两种来自狭叶重楼的新的高度氧化螺甾烷醇皂苷。

Two New Highly Oxygenated Spirostanol Saponins from Paris polyphylla var. stenophylla.

作者信息

Jin Ling-Yu, Lu Ting-Xiang, Qin Xu-Jie, Ni Wei, Yan Huan, Chen Yu, Liu Hui, He Hong-Ping, Liu Hai-Yang

机构信息

College of Pharmacy and Chemistry, Dali University, Dali, 671000, China.

State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, 650201, China.

出版信息

Nat Prod Bioprospect. 2016 Aug;6(4):205-10. doi: 10.1007/s13659-016-0102-x. Epub 2016 Jun 2.

DOI:10.1007/s13659-016-0102-x
PMID:27255683
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4940253/
Abstract

Phytochemical investigation of the rhizomes of Paris polyphylla var. stenophylla led to the isolation of two new highly oxygenated spirostanol saponins, named paristenosides A (1) and B (2), together with seven known compounds. Their structures were established mainly on the base of NMR spectroscopic techniques and mass spectrometry, as well as chemical methods. In addition, the cytotoxicity of the two new saponins was tested. Two new highly oxygenated spirostanol saponins, paristenosides A (1) and B (2), were isolated from the rhizomes of Paris polyphylla var. stenophylla. Their structures were established mainly based on NMR spectroscopic techniques and mass spectrometry, as well as chemical methods.

摘要

对狭叶重楼根茎进行植物化学研究,从中分离出两种新的高度氧化的螺甾烷醇皂苷,命名为狭叶重楼皂苷A(1)和B(2),以及七种已知化合物。它们的结构主要基于核磁共振光谱技术、质谱以及化学方法确定。此外,还测试了这两种新皂苷的细胞毒性。从狭叶重楼根茎中分离出两种新的高度氧化的螺甾烷醇皂苷,狭叶重楼皂苷A(1)和B(2)。它们的结构主要基于核磁共振光谱技术、质谱以及化学方法确定。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1779/4940253/c638a82d0033/13659_2016_102_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1779/4940253/89a6e0508407/13659_2016_102_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1779/4940253/73e3fb96984d/13659_2016_102_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1779/4940253/c638a82d0033/13659_2016_102_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1779/4940253/89a6e0508407/13659_2016_102_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1779/4940253/73e3fb96984d/13659_2016_102_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1779/4940253/c638a82d0033/13659_2016_102_Fig3_HTML.jpg

相似文献

1
Two New Highly Oxygenated Spirostanol Saponins from Paris polyphylla var. stenophylla.两种来自狭叶重楼的新的高度氧化螺甾烷醇皂苷。
Nat Prod Bioprospect. 2016 Aug;6(4):205-10. doi: 10.1007/s13659-016-0102-x. Epub 2016 Jun 2.
2
Steroid and triterpenoid saponins from the rhizomes of Paris polyphylla var. stenophylla.石菖蒲根茎中的甾体和三萜皂苷。
Chin J Nat Med. 2023 Oct;21(10):789-800. doi: 10.1016/S1875-5364(23)60486-8.
3
Seeing the light: Shifting from wild rhizomes to extraction of active ingredients from above-ground parts of Paris polyphylla var. yunnanensis.看到曙光:从野生块茎转向从云南重楼地上部分提取有效成分。
J Ethnopharmacol. 2018 Oct 5;224:134-139. doi: 10.1016/j.jep.2018.05.028. Epub 2018 May 21.
4
Cytotoxic Steroidal Saponins Containing a Rare Fructosyl from the Rhizomes of var. .含有罕见果糖基的细胞毒甾体皂甙 var. 的根茎
Int J Mol Sci. 2023 Apr 12;24(8):7149. doi: 10.3390/ijms24087149.
5
[Separation and structural elucidation of C25 epimers of furostanol saponin from aerial parts of Paris polyphylla var. chinensis].[华重楼地上部分呋甾烷醇皂苷C25差向异构体的分离与结构鉴定]
Zhongguo Zhong Yao Za Zhi. 2021 Aug;46(16):4023-4033. doi: 10.19540/j.cnki.cjcmm.20210623.302.
6
Triterpenoid saponins from rhizomes of Paris polyphylla var. yunnanensis.云南重楼根茎中的三萜皂苷。
Carbohydr Res. 2013 Mar 7;368:1-7. doi: 10.1016/j.carres.2012.11.027. Epub 2012 Dec 8.
7
[Isolation and identification of major steroidal saponins of Paris polyphylla Smith var stenophylla Franch].[狭叶重楼主要甾体皂苷的分离与鉴定]
Sichuan Da Xue Xue Bao Yi Xue Ban. 2008 May;39(3):485-8.
8
[Determination of five steroidal saponins in Paridis Rhizoma and its adulterants as well as consideration on its quantitative method described in Chinese Pharmacopoeia (2015 edition)].[重楼及其混伪品中5种甾体皂苷的测定以及对《中国药典》(2015年版)中其定量方法的思考]
Zhongguo Zhong Yao Za Zhi. 2020 Apr;45(8):1745-1755. doi: 10.19540/j.cnki.cjcmm.20200330.201.
9
[Chemical constituents of steroidal saponins in rhizome of Paris polyphylla var. yunnanensis cultured in vitro].[滇重楼离体培养根茎中甾体皂苷类化学成分研究]
Zhongguo Zhong Yao Za Zhi. 2021 Oct;46(19):4936-4944. doi: 10.19540/j.cnki.cjcmm.20210722.101.
10
Qualitative and quantitative analysis of steroidal saponins in crude extracts from Paris polyphylla var. yunnanensis and P. polyphylla var. chinensis by high performance liquid chromatography coupled with mass spectrometry.采用高效液相色谱-质谱联用法对滇重楼和七叶一枝花粗提物中的甾体皂苷进行定性和定量分析。
J Pharm Biomed Anal. 2010 Jan 5;51(1):114-24. doi: 10.1016/j.jpba.2009.08.020. Epub 2009 Aug 25.

引用本文的文献

1
Population Genetic Analysis of var. Based on cpDNA Fragments.基于 cpDNA 片段的 var. 种群遗传分析。
Genes (Basel). 2023 Sep 2;14(9):1754. doi: 10.3390/genes14091754.
2
Untiring Researches for Alternative Resources of Rhizoma Paridis.重楼替代资源的不懈研究
Nat Prod Bioprospect. 2018 Aug;8(4):265-278. doi: 10.1007/s13659-018-0179-5. Epub 2018 Jul 4.

本文引用的文献

1
Steroidal saponins from stems and leaves of Paris polyphylla var. yunnanensis.滇重楼茎叶中的甾体皂苷。
Phytochemistry. 2016 Jan;121:20-9. doi: 10.1016/j.phytochem.2015.10.008. Epub 2015 Nov 3.
2
Steroidal saponins with induced platelet aggregation activity from the aerial parts of Paris verticillata.从七叶一枝花地上部分分离得到的具有诱导血小板聚集活性的甾体皂苷。
Steroids. 2014 Dec;92:90-5. doi: 10.1016/j.steroids.2014.09.008.
3
C(22)-steroidal lactone glycosides from stems and leaves of Paris polyphylla var. yunnanensis.
云南重楼茎和叶中的 C(22)-甾体皂甙糖苷。
Fitoterapia. 2013 Jan;84:248-51. doi: 10.1016/j.fitote.2012.12.007. Epub 2012 Dec 20.
4
Steroidal saponins with antimicrobial activity from stems and leaves of Paris polyphylla var. yunnanensis.具有抗菌活性的甾体皂苷类化合物来源于云南重楼的茎和叶。
Steroids. 2012 Oct;77(12):1242-8. doi: 10.1016/j.steroids.2012.07.007. Epub 2012 Jul 28.
5
Polyhydroxylated steroidal glycosides from Paris polyphylla.重楼属植物中的多羟基甾体糖苷。
J Nat Prod. 2012 Jun 22;75(6):1201-5. doi: 10.1021/np300045g. Epub 2012 Jun 4.
6
Antitumor and antimetastatic activities of Rhizoma Paridis saponins.重楼皂苷的抗肿瘤和抗转移活性。
Steroids. 2009 Nov-Dec;74(13-14):1051-6. doi: 10.1016/j.steroids.2009.08.004. Epub 2009 Aug 20.
7
Steroidal saponins from the rhizomes of Paris delavayi.大理重楼根茎中的甾体皂苷
Steroids. 2009 Oct;74(10-11):809-13. doi: 10.1016/j.steroids.2009.04.012. Epub 2009 May 15.
8
Proteomic analysis of anti-tumor effects by Rhizoma Paridis total saponin treatment in HepG2 cells.
J Ethnopharmacol. 2008 Nov 20;120(2):129-37. doi: 10.1016/j.jep.2008.07.030. Epub 2008 Aug 6.
9
Antifungal saponins from Paris polyphylla Smith.来自七叶一枝花的抗真菌皂苷。
Planta Med. 2008 Sep;74(11):1397-402. doi: 10.1055/s-2008-1081345. Epub 2008 Aug 26.
10
[Isolation and identification of major steroidal saponins of Paris polyphylla Smith var stenophylla Franch].[狭叶重楼主要甾体皂苷的分离与鉴定]
Sichuan Da Xue Xue Bao Yi Xue Ban. 2008 May;39(3):485-8.