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眼眶间叶性软骨肉瘤:CT与MRI的影像特征

Mesenchymal chondrosarcoma of the orbit: imaging features of CT and MRI.

作者信息

Tsuchiya Mitsuteru, Masui Takayuki, Otsuki Yoshiro, Sakahara Harumi

机构信息

1 Department of Radiology, Seirei Hamamatsu General Hospital , Hamamatsu, Shizuoka , Japan.

2 Department of Pathology, Seirei Hamamatsu General Hospital , Hamamatsu, Shizuoka , Japan.

出版信息

Br J Radiol. 2018 Oct;91(1090):20170579. doi: 10.1259/bjr.20170579. Epub 2018 Jul 25.

Abstract

OBJECTIVE

: Mesenchymal chondrosarcoma (MCS) of the orbit is a rare and aggressive form of chondrosarcoma. The purpose of this study was to retrospectively identify the imaging features of mesenchymal chondrosarcoma of the orbit.

METHODS

: This study included five patients with histologically confirmed MCS of the orbit who had undergone either CT, MRI, or both. Images were evaluated for the following: location, size, margin, CT density and presence or absence of calcification and/or ossification, MRI findings including dynamic contrast-enhancement and time-intensity curves.

RESULTS

: CT was performed in four of the five patients, and all four (100%) demonstrated calcification and ossification of the mass. MRI was performed in all five patients. In two patients (40%), the mass demonstrated areas of hyperintensity on T weighted images.

CONCLUSION

: The presence of a well-defined, orbital mass with calcification and ossification on CT and, marked heterogenous enhancement and a rapid-washout pattern on dynamic MRI indicate a high probability of MCS of the orbit. In addition, MCS of the orbit can demonstrate areas of hyperintensity on T weighted images, representing bone marrow fat tissue of ossification.

ADVANCES IN KNOWLEDGE

: MCS of the orbit is a highly malignant tumor, and early diagnosis by imaging is important. Radiologists should be aware of the imaging features of MCS of the orbit.

摘要

目的

眼眶间叶性软骨肉瘤(MCS)是一种罕见且侵袭性强的软骨肉瘤形式。本研究的目的是回顾性确定眼眶间叶性软骨肉瘤的影像学特征。

方法

本研究纳入了5例经组织学证实为眼眶MCS的患者,这些患者均接受了CT、MRI检查或两者都做了检查。对图像进行如下评估:位置、大小、边缘、CT密度以及有无钙化和/或骨化,MRI表现包括动态对比增强和时间-强度曲线。

结果

5例患者中有4例进行了CT检查,所有4例(100%)均显示肿块有钙化和骨化。5例患者均进行了MRI检查。2例患者(40%)肿块在T加权图像上表现为高信号区。

结论

CT上出现边界清晰、有钙化和骨化的眼眶肿块,以及动态MRI上明显的不均匀强化和快速廓清模式,提示眼眶MCS的可能性很大。此外,眼眶MCS在T加权图像上可显示高信号区,代表骨化的骨髓脂肪组织。

知识进展

眼眶MCS是一种高度恶性肿瘤,通过影像学进行早期诊断很重要。放射科医生应了解眼眶MCS的影像学特征。

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Mesenchymal chondrosarcoma of the orbit: imaging features of CT and MRI.眼眶间叶性软骨肉瘤:CT与MRI的影像特征
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本文引用的文献

2
Characterization of orbital masses by multiparametric MRI.通过多参数磁共振成像对眼眶肿物进行特征描述。
Eur J Radiol. 2016 Feb;85(2):324-36. doi: 10.1016/j.ejrad.2015.11.041. Epub 2015 Dec 4.
5
Mesenchymal chondrosarcoma of the orbit--case report.眼眶间叶性软骨肉瘤——病例报告
Neurol Med Chir (Tokyo). 2012;52(10):747-50. doi: 10.2176/nmc.52.747.
8
Mesenchymal chondrosarcoma of the orbit.眼眶间叶性软骨肉瘤
Orbit. 2012 Apr;31(2):126-8. doi: 10.3109/01676830.2011.638097.
9
Mesenchymal chondrosarcoma of the orbit: CT and MRI findings.眼眶间叶性软骨肉瘤:CT 和 MRI 表现。
Clin Radiol. 2012 Apr;67(4):346-51. doi: 10.1016/j.crad.2011.10.004. Epub 2011 Dec 16.

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