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眼眶间叶性软骨肉瘤:CT与MRI的影像特征

Mesenchymal chondrosarcoma of the orbit: imaging features of CT and MRI.

作者信息

Tsuchiya Mitsuteru, Masui Takayuki, Otsuki Yoshiro, Sakahara Harumi

机构信息

1 Department of Radiology, Seirei Hamamatsu General Hospital , Hamamatsu, Shizuoka , Japan.

2 Department of Pathology, Seirei Hamamatsu General Hospital , Hamamatsu, Shizuoka , Japan.

出版信息

Br J Radiol. 2018 Oct;91(1090):20170579. doi: 10.1259/bjr.20170579. Epub 2018 Jul 25.

DOI:10.1259/bjr.20170579
PMID:29975155
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6350477/
Abstract

OBJECTIVE

: Mesenchymal chondrosarcoma (MCS) of the orbit is a rare and aggressive form of chondrosarcoma. The purpose of this study was to retrospectively identify the imaging features of mesenchymal chondrosarcoma of the orbit.

METHODS

: This study included five patients with histologically confirmed MCS of the orbit who had undergone either CT, MRI, or both. Images were evaluated for the following: location, size, margin, CT density and presence or absence of calcification and/or ossification, MRI findings including dynamic contrast-enhancement and time-intensity curves.

RESULTS

: CT was performed in four of the five patients, and all four (100%) demonstrated calcification and ossification of the mass. MRI was performed in all five patients. In two patients (40%), the mass demonstrated areas of hyperintensity on T weighted images.

CONCLUSION

: The presence of a well-defined, orbital mass with calcification and ossification on CT and, marked heterogenous enhancement and a rapid-washout pattern on dynamic MRI indicate a high probability of MCS of the orbit. In addition, MCS of the orbit can demonstrate areas of hyperintensity on T weighted images, representing bone marrow fat tissue of ossification.

ADVANCES IN KNOWLEDGE

: MCS of the orbit is a highly malignant tumor, and early diagnosis by imaging is important. Radiologists should be aware of the imaging features of MCS of the orbit.

摘要

目的

眼眶间叶性软骨肉瘤(MCS)是一种罕见且侵袭性强的软骨肉瘤形式。本研究的目的是回顾性确定眼眶间叶性软骨肉瘤的影像学特征。

方法

本研究纳入了5例经组织学证实为眼眶MCS的患者,这些患者均接受了CT、MRI检查或两者都做了检查。对图像进行如下评估:位置、大小、边缘、CT密度以及有无钙化和/或骨化,MRI表现包括动态对比增强和时间-强度曲线。

结果

5例患者中有4例进行了CT检查,所有4例(100%)均显示肿块有钙化和骨化。5例患者均进行了MRI检查。2例患者(40%)肿块在T加权图像上表现为高信号区。

结论

CT上出现边界清晰、有钙化和骨化的眼眶肿块,以及动态MRI上明显的不均匀强化和快速廓清模式,提示眼眶MCS的可能性很大。此外,眼眶MCS在T加权图像上可显示高信号区,代表骨化的骨髓脂肪组织。

知识进展

眼眶MCS是一种高度恶性肿瘤,通过影像学进行早期诊断很重要。放射科医生应了解眼眶MCS的影像学特征。

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Characterization of orbital masses by multiparametric MRI.通过多参数磁共振成像对眼眶肿物进行特征描述。
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Orbital neoplasms in adults: clinical, radiologic, and pathologic review.成人眼眶肿瘤:临床、放射学和病理学回顾。
Radiographics. 2013 Oct;33(6):1739-58. doi: 10.1148/rg.336135502.
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Extraskeletal intraspinal mesenchymal chondrosarcoma; 18F-FDG PET/CT finding.骨外椎管内间叶性软骨肉瘤;18F-FDG PET/CT 表现。
Clin Nucl Med. 2014 Jan;39(1):e64-6. doi: 10.1097/RLU.0b013e3182815cd5.
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