Department of Neurology & Neurological Research, St. Vincent's Hospital Melbourne, P.O. Box 2900, Fitzroy, 3065, Melbourne, Australia.
Department of Medicine, The University of Melbourne, Australia.
Muscle Nerve. 2018 Nov;58(5):665-670. doi: 10.1002/mus.26290. Epub 2018 Sep 19.
The single-fiber F-wave (SFF-wave) technique assesses the entire length of single motor fibers using a concentric needle. Herein we investigated the utility of this approach in the detection of early diabetes-related neuropathy, and compared it with the use of conventional surface F waves (CF waves).
Sixteen patients with diabetes and either no neuropathy or mild neuropathy were assessed and compared with 16 age- and height-matched control participants.
Both CF and SFF waves were abnormal in all 5 patients who had mild neuropathy. However, SFF waves demonstrated subclinical abnormalities in 7 of 11 patients (64%) with no neuropathy, whereas only 2 of these patients (18%) had prolonged CF waves. Minimum F-wave latency was comparable between techniques, but maximum SFF-wave latency was more frequently prolonged, as these delayed motor units were better isolated, rather than buried among summated CF-wave responses.
SFF waves highlight the segmental involvement in diabetic neuropathy, and use of the SFF-wave technique detects more abnormalities than with CF waves. Muscle Nerve 58: 665-670, 2018.
单纤维 F 波（SFF 波）技术使用同心针评估单个运动纤维的全长。在此，我们研究了该方法在检测早期糖尿病相关神经病变中的效用，并将其与传统的表面 F 波（CF 波）进行了比较。
评估了 16 名患有糖尿病且无神经病变或轻度神经病变的患者，并与 16 名年龄和身高匹配的对照参与者进行了比较。
所有 5 名轻度神经病变患者的 CF 和 SFF 波均异常。然而，SFF 波在 11 名无神经病变患者中的 7 名（64%）中显示出亚临床异常，而这些患者中只有 2 名（18%）的 CF 波延长。两种技术的最小 F 波潜伏期相当，但 SFF 波最大潜伏期更常延长，因为这些延迟的运动单位被更好地分离，而不是埋藏在总和 CF 波反应中。
SFF 波突出了糖尿病性神经病的节段性受累，并且 SFF 波技术的使用比 CF 波检测到更多的异常。肌肉神经 58:665-670,2018。
