韩国老年男性中高风险饮酒与代谢综合征及其组分的关联：2010 - 2012年韩国国民健康与营养检查调查
Association of High-Risk Drinking with Metabolic Syndrome and Its Components in Elderly Korean Men: The Korean National Health and Nutrition Examination Survey 2010-2012.
作者信息
Kim Ji-Hyun, Ha Jeong-Im, Park Jae-Min, Lee Ji Sun, Ahn Ah-Leum, Oh Eun-Jung, Choi Jae-Kyung, Kweon Hyuk-Jung, Cho Dong-Yung
机构信息
Department of Family Medicine, Konkuk University Medical Center, Seoul, Korea.
Department of Family Medicine, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.
出版信息
Korean J Fam Med. 2018 Jul;39(4):233-238. doi: 10.4082/kjfm.17.0024. Epub 2018 Jul 6.
BACKGROUND
Previous studies have examined the association between alcohol consumption and metabolic syndrome (MetS) in adults, but studies in the elderly are lacking. We examined the relationship between high-risk alcohol consumption and MetS in elderly Korean men using the Alcohol Use Disorders Identification Test (AUDIT) questionnaire from the 2010-2012 Korean National Health and Nutrition Examination Survey.
METHODS
Among 25,534 subjects, 2,807 were men >60 years of age; after exclusions, we included 2,088 men in the final analysis. We categorized the study participants into three groups according to AUDIT score: low risk (0-7), intermediate risk (8-14), and high risk (≥15 points).
RESULTS
Among the study population, 17.0% of the men were high-risk drinkers, who had the highest mean waist circumference, systolic and diastolic blood pressure (BP), fasting plasma glucose (FPG), and triglyceride (TG) levels. The overall prevalence of MetS was 41.9% in the elderly men, and it was significantly higher in the group with high (48.3%) versus low (31.9%) AUDIT scores. The prevalence of MetS components (elevated BP, high FPG, high TG, and low high-density lipoprotein cholesterol) was associated with a high AUDIT score. The odds ratios (95% confidence interval) of the high-risk group for MetS, elevated BP, and high TG were 1.40 (1.03-1.89), 1.82 (1.28- 2.60), and 1.77 (1.30-2.41) after adjustment for confounding variables.
CONCLUSION
AUDIT score was correlated with most MetS components in elderly Korean men.
背景
既往研究已探讨了成人饮酒与代谢综合征（MetS）之间的关联，但针对老年人的研究较少。我们使用2010 - 2012年韩国国民健康与营养检查调查中的酒精使用障碍识别测试（AUDIT）问卷，研究了韩国老年男性中高危饮酒与MetS之间的关系。
方法
在25534名受试者中，有2807名年龄大于60岁的男性；排除部分受试者后，最终分析纳入了2088名男性。我们根据AUDIT评分将研究参与者分为三组：低风险（0 - 7分）、中度风险（8 - 14分）和高风险（≥15分）。
结果
在研究人群中，17.0%的男性为高危饮酒者，他们的平均腰围、收缩压和舒张压（BP）、空腹血糖（FPG）以及甘油三酯（TG）水平最高。老年男性中MetS的总体患病率为41.9%，AUDIT评分高（48.3%）的组显著高于评分低（31.9%）的组。MetS各组分（血压升高、FPG升高、TG升高和高密度脂蛋白胆固醇降低）的患病率与高AUDIT评分相关。在调整混杂变量后，高危组患MetS、血压升高和TG升高的比值比（95%置信区间）分别为1.40（1.03 - 1.89）、1.82（1.28 - 2.60）和1.77（1.30 - 2.41）。
结论
AUDIT评分与韩国老年男性的大多数MetS组分相关。
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