Kalamangalam Giridhar P, Pohlmann-Eden Bernhard
Department of Neurology, University of Florida, Gainesville, Florida, U.S.A.
Brain Repair Center, Life Science Research Institute, Dalhousie University, Halifax, NS, Canada.
J Clin Neurophysiol. 2018 Jul;35(4):274-278. doi: 10.1097/WNP.0000000000000447.
The term "ictal-interictal" continuum has seen wide adoption in the critical care EEG domain, referring to the presence of abnormal periodic activity on the scalp EEG variably associated with seizures. The historical origin of the ictal-interictal continuum concept is discussed with a review of known and surmised physiological mechanisms for their origin and relationship to seizures. Therapeutic approaches to patients exhibiting ictal-interictal continuum EEG patterns are reviewed, and some open scientific questions highlighted. Further understanding of the ictal-interictal continuum is likely to significantly improve the care of the critically ill neurological patient.
“发作期 - 发作间期”连续体这一术语在重症监护脑电图领域已被广泛采用，它指的是头皮脑电图上存在与癫痫发作可变相关的异常周期性活动。本文讨论了发作期 - 发作间期连续体概念的历史起源，并回顾了其已知和推测的生理机制，包括其起源以及与癫痫发作的关系。本文还综述了针对呈现发作期 - 发作间期连续体脑电图模式患者的治疗方法，并突出了一些尚未解决的科学问题。对发作期 - 发作间期连续体的进一步理解可能会显著改善对重症神经疾病患者的护理。
