Li Wei, Pan Yu, Yang Qi, Guo Zheng-Gui, Yue Qi, Meng Qing-Gang
Department of Medical Science, Institute of Harbin, The First Hospital of Harbin City, Harbin Medical University Department of Study Center, The First Affiliated Hospital of Harbin Medical University Department of Study Center, The Fourth Affiliated Hospital of Harbin Medical University, Harbin, China.
Medicine (Baltimore). 2018 Jul;97(27):e11418. doi: 10.1097/MD.0000000000011418.
This retrospective study investigated the effect and safety of extracorporeal shockwave therapy (ESWT) for treatment of knee osteoarthritis (KOA).In this retrospective study, 105 patients with KOA were included. Of those, 60 patients underwent ESWT, whereas 45 patients received laser therapy. Effect was measured by the Numeric Rating Scale (NRS) and Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC). In addition, adverse events (AEs) were also recorded in this study. All outcome measurements were evaluated at the end of weeks 1, 6, and 12.Compared with the laser therapy, ESWT showed greater effect in KOA symptoms relief with regard to NRS, WOMAC total, and its subscores at week 6 (P < .05) and week 12 (P < .01) after treatment. No AE, however, occurred in both groups.The results of this retrospective study found that ESWT may be efficacious and safe for the treatment of patients with KOA. It, however, had an intrinsic limitation as a retrospective study. Prospective study with larger sample size is still needed to warrant the result of this study in the future.
这项回顾性研究调查了体外冲击波疗法（ESWT）治疗膝关节骨关节炎（KOA）的疗效和安全性。在这项回顾性研究中，纳入了105例KOA患者。其中，60例患者接受了ESWT治疗，而45例患者接受了激光治疗。通过数字评分量表（NRS）和西安大略和麦克马斯特大学骨关节炎指数（WOMAC）来衡量疗效。此外，本研究还记录了不良事件（AE）。所有结局指标均在第1、6和12周结束时进行评估。与激光治疗相比，ESWT在治疗后第6周（P<0.05）和第12周（P<0.01）时，在缓解KOA症状方面，在NRS、WOMAC总分及其子评分方面显示出更大的效果。然而，两组均未发生AE。这项回顾性研究的结果发现，ESWT治疗KOA患者可能有效且安全。然而，作为一项回顾性研究，它有其内在局限性。未来仍需要进行更大样本量的前瞻性研究来证实本研究的结果。
