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基于短信的干预措施成本分析,以促进肯尼亚卡车司机和性工作者进行 HIV 自检。

Costing analysis of an SMS-based intervention to promote HIV self-testing amongst truckers and sex workers in Kenya.

机构信息

Health Economics and HIV and AIDS Research Division, University of KwaZulu-Natal, Durban, South Africa.

North Star Alliance, Nairobi, Kenya.

出版信息

PLoS One. 2018 Jul 6;13(7):e0197305. doi: 10.1371/journal.pone.0197305. eCollection 2018.

Abstract

OBJECTIVE

HIV testing rates in many sub-Saharan African countries have remained suboptimal, and there is an urgent need to explore strategic yet cost-effective approaches to increase the uptake of HIV testing, especially among high-risk populations.

METHODS

A costing analysis was conducted for a randomized controlled trial (RCT) with male truckers and female sex workers (FSWs) registered in the electronic health record system (EHRS) of the North Star Alliance, which offers healthcare services at major transit hubs in Southern and East Africa. The RCT selected a sample of truckers and FSWs who were irregular HIV testers, according to the EHRS, and evaluated the effect of SMSs promoting the availability of HIV self-testing (HIVST) kits in Kenyan clinics (intervention program) versus a general SMS reminding clients to test for HIV (enhanced and standard program) on HIV testing rates. In this paper, we calculated costs from a provider perspective using a mixed-methods approach to identify, measure, and value the resources utilized within the intervention and standard programs. The results of the analysis reflect the cost per client tested.

RESULTS

The cost of offering HIVST was calculated to be double that of routine facility-based testing (USD 10.13 versus USD 5.01 per client tested), primarily due to the high price of the self-test kit. In the two study arms that only offered provider-administered HIV testing in the clinic, only 1% of truckers and 6% of FSWs tested during the study period, while in the intervention arm, which also offered HST, approximately 4% of truckers and 11% of FSWs tested. These lower than expected outcomes resulted in relatively high cost per client estimates for all three study arms. Within the intervention arm, 65% of truckers and 72% of FSWs who tested chose the HIVST option. However, within the intervention arm, the cost per additional client tested was lower for FSWs than for truckers, at USD 0.15 per additional client tested versus USD 0.58 per additional client tested, driven primarily by the higher response rates.

CONCLUSION

Whilst the availability of HIVST increased HIV testing among both truckers and FSWs, the cost of providing HIVST is higher than that of a routine health facility-based test, driven primarily by the price of the HIV self-test kit. Future research needs to identify strategies which increase demand for HIVST, and determine whether these strategies and the subsequent increased demand for HIVST are cost-effective in relation to the conventional facility based testing currently available.

摘要

目的

在许多撒哈拉以南非洲国家,艾滋病毒检测率仍然不理想,因此迫切需要探索具有战略意义且具有成本效益的方法来提高艾滋病毒检测率,尤其是在高危人群中。

方法

对在南非和东非主要过境点提供医疗服务的北方之星联盟电子健康记录系统(EHRS)中登记的男性卡车司机和女性性工作者(FSW)进行了一项成本分析,该联盟进行了一项随机对照试验(RCT)。该 RCT 根据 EHRS 选择了一组艾滋病毒检测不规则的卡车司机和 FSW 作为样本,并评估了在肯尼亚诊所提供艾滋病毒自我检测(HIVST)试剂盒的短信(干预方案)与仅提供提醒客户进行艾滋病毒检测的一般短信(增强和标准方案)对艾滋病毒检测率的影响。在本文中,我们从提供者的角度使用混合方法计算成本,以确定、衡量和评估干预和标准方案中使用的资源。分析结果反映了每位接受检测的客户的成本。

结果

提供 HIVST 的成本被计算为常规基于设施的检测的两倍(每位接受检测的客户 10.13 美元与 5.01 美元),这主要是由于自我检测试剂盒的高价格所致。在仅在诊所提供提供者管理的艾滋病毒检测的两个研究臂中,只有 1%的卡车司机和 6%的 FSW 在研究期间接受了检测,而在提供 HST 的干预臂中,大约 4%的卡车司机和 11%的 FSW 接受了检测。这些低于预期的结果导致所有三个研究臂的每位接受检测的客户的估计成本相对较高。在干预臂中,接受检测的卡车司机中有 65%和 FSW 中有 72%选择了 HIVST 选项。然而,在干预臂中,与卡车司机相比,每增加一位接受检测的客户的成本更低,每增加一位接受检测的客户的成本为 0.15 美元,而每增加一位接受检测的客户的成本为 0.58 美元,这主要是由于较高的响应率所致。

结论

虽然 HIVST 的提供增加了卡车司机和 FSW 中的艾滋病毒检测,但提供 HIVST 的成本高于常规卫生机构的基础检测,这主要是由于 HIV 自我检测试剂盒的价格所致。未来的研究需要确定增加 HIVST 需求的策略,并确定这些策略以及随后对 HIVST 的需求增加是否相对于目前可获得的常规基于设施的检测具有成本效益。

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