Kim Jong-Hoon
Department of Physiology, College of Veterinary Medicine, Chonbuk National University, Iksan, Republic of Korea.
J Ginseng Res. 2018 Jul;42(3):264-269. doi: 10.1016/j.jgr.2017.10.004. Epub 2017 Oct 21.
, also called Asian or Korean ginseng, has long been traditionally used in Korea and China to treat various diseases. The major active ingredients of are ginsenosides, which have been shown to have a variety of therapeutic effects, including antioxidation, anti-inflammatory, vasorelaxation, antiallergic, antidiabetic, and anticancer. To date, approximately 40 ginsenoside components have been reported. Current research is concentrating on using a single ginseng compound, one of the ginsenosides, instead of the total ginseng compounds, to determine the mechanisms of ginseng and ginsenosides. Recent and results show that ginseng has beneficial effects on cardiac and vascular diseases through efficacy, including antioxidation, control of vasomotor function, modulation of ion channels and signal transduction, improvement of lipid profiles, adjustment of blood pressure, improvement in cardiac function, and reduction in platelet adhesion. This review aims to provide valuable information on the traditional uses of ginseng and ginsenosides, their therapeutic applications in animal models and humans, and the pharmacological action of ginseng and ginsenosides.
人参，也被称为亚洲人参或高丽参，长期以来在韩国和中国传统上用于治疗各种疾病。人参的主要活性成分是人参皂苷，已显示出具有多种治疗作用，包括抗氧化、抗炎、血管舒张、抗过敏、抗糖尿病和抗癌。迄今为止，已报道了约40种人参皂苷成分。目前的研究集中在使用单一的人参化合物，即其中一种人参皂苷，而不是整个人参化合物，来确定人参和人参皂苷的作用机制。最近的[具体研究]和[具体研究]结果表明，人参通过抗氧化、控制血管运动功能、调节离子通道和信号转导、改善脂质谱、调节血压、改善心脏功能以及减少血小板粘附等功效，对心脏和血管疾病具有有益作用。本综述旨在提供有关人参和人参皂苷的传统用途、它们在动物模型和人类中的治疗应用以及人参和人参皂苷的药理作用的有价值信息。
