Karani J, Fletcher M, Brinkley D, Dawson J L, Williams R, Nunnerley H
Clin Radiol. 1985 Nov;36(6):603-6. doi: 10.1016/s0009-9260(85)80242-7.
Curative surgery is not possible in the vast majority of patients who present with hilar cholangiocarcinoma. Palliative therapy to relieve jaundice, either at laparotomy or percutaneously, is therefore necessary. The mean survival of these patients is of the order of 8.5 months (Wheeler et al., 1981). We report a significant increase in mean survival to 16.8 months in patients treated with internal biliary drainage when combined with local irradiation to the tumour with iridium-192.
对于绝大多数出现肝门部胆管癌的患者而言，根治性手术是无法实现的。因此，无论是通过剖腹手术还是经皮穿刺，进行缓解黄疸的姑息性治疗都是必要的。这些患者的平均生存期约为8.5个月（惠勒等人，1981年）。我们报告称，采用内胆管引流并结合使用铱-192对肿瘤进行局部照射的患者，其平均生存期显著延长至16.8个月。
