Max Planck Institute for Developmental Biology, Department of Molecular Biology, Tübingen, Germany.
Department of Forest Genetics and Plant Physiology, Umeå Plant Science Centre, Swedish University for Agricultural Sciences, Umeå, Sweden.
Nat Plants. 2018 Aug;4(8):534-539. doi: 10.1038/s41477-018-0176-z. Epub 2018 Jul 9.
Recent findings suggest that alternative splicing has a critical role in controlling the responses of plants to temperature variations. However, alternative splicing factors in plants are largely uncharacterized. Here we establish the putative splice regulator, PORCUPINE (PCP), as temperature-specific regulator of development in Arabidopsis thaliana. Our findings point to the misregulation of WUSCHEL and CLAVATA3 as the possible cause for the meristem defects affecting the pcp-1 loss-of-function mutants at low temperatures.
最近的研究结果表明,可变剪接在控制植物对温度变化的反应方面起着关键作用。然而,植物中的可变剪接因子在很大程度上还没有被描述。在这里,我们将假定的剪接调节剂 PORCUPINE(PCP)确定为拟南芥中温度特异性发育的调节剂。我们的研究结果指出,WUSCHEL 和 CLAVATA3 的失调可能是导致 pcp-1 功能缺失突变体在低温下分生组织缺陷的原因。