Lee Namhoon, Baek Kiook, Park Soohyun, Hwang Inho, Chung Insung, Choi Wonil, Jung Hyera, Lee Miyoung, Yang Seonhee
1Department of Occupational and Environmental Medicine, Keimyung University Dongsan Medical Center, 1095 Dalgubeol-daero, Dalseo-gu, Daegu, 42601 South Korea.
Nano Convergence Practical Application Center, Daegu, South Korea.
Ann Occup Environ Med. 2018 Jun 4;30:37. doi: 10.1186/s40557-018-0248-6. eCollection 2018.
Using analysis of air samples from the workplace, we report on one case of pneumoconiosis in an individual who has been working in a polytetrafluoroethylene (PTFE) spraying process for 28 years.
The patient was diagnosed with granulomatous lung disease caused by PTFE using computed tomography (CT), lung biopsy and electron microscopy. To assess the qualitative and quantitative exposure to PTFE in workplace, Fourier transform infrared spectroscopy (FT-IR), energy-dispersive X-ray spectroscopy (EDX) and thermogravimetric analysis (TGA) were performed on air samples from the workplace. The presence of PTFE particles was confirmed, and the airborne concentration of PTFE was estimated to be 0.75 mg/m.
This case demonstrates that long-term exposure to PTFE spraying can cause granulomatous lung lesions such as pneumoconiosis; such lesions appear to be caused not by the degradation products of PTFE from high temperatures but by spraying the particles of PTFE. Along with air-sampling analysis, we suggest monitoring the concentration of airborne PTFE particles related to chronic lung disease.
通过对工作场所空气样本的分析，我们报告了一例在聚四氟乙烯（PTFE）喷涂工艺中工作28年的个体患尘肺病的病例。
使用计算机断层扫描（CT）、肺活检和电子显微镜检查，该患者被诊断为聚四氟乙烯引起的肉芽肿性肺病。为了评估工作场所中聚四氟乙烯的定性和定量暴露情况，对工作场所的空气样本进行了傅里叶变换红外光谱（FT-IR）、能量色散X射线光谱（EDX）和热重分析（TGA）。证实了聚四氟乙烯颗粒的存在，估计空气中聚四氟乙烯的浓度为0.75毫克/立方米。
该病例表明，长期接触聚四氟乙烯喷涂可导致尘肺病等肉芽肿性肺部病变；此类病变似乎不是由高温下聚四氟乙烯的降解产物引起的，而是由聚四氟乙烯颗粒的喷涂引起的。除了空气采样分析外，我们建议监测与慢性肺病相关的空气中聚四氟乙烯颗粒的浓度。
