Institute of Fluorescent Probes for Biological Imaging, School of Chemistry and Chemical Engineering, School of Materials Science and Engineering, University of Jinan, Jinan, Shandong 250022, P. R. China.
Analyst. 2018 Jul 23;143(15):3555-3559. doi: 10.1039/c8an00842f.
A H2O2-responsive fluorescent chemosensor (CNBE) with a ratiometric emission signal was elaborately designed and synthesized. The ratio signal of the chemosensor was manipulated by an interplaying ICT-activated FRET mechanism. The ratiometric fluorescence imaging was successfully applied to detect H2O2 using CNBE in living cells and zebrafish.
精心设计并合成了一种具有比率发射信号的 H2O2 响应型荧光化学传感器（CNBE）。化学传感器的比率信号通过相互作用的 ICT 激活 FRET 机制进行调控。使用 CNBE 在活细胞和斑马鱼中成功地进行了比率荧光成像以检测 H2O2。
