Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, 149 13th St., Charlestown, MA, 02129, USA.
University of Naples "Parthenope", Naples, Italy.
Eur J Nucl Med Mol Imaging. 2018 Nov;45(12):2147-2154. doi: 10.1007/s00259-018-4084-2. Epub 2018 Jul 11.
To compare the clinical performance of upper abdominal PET/DCE-MRI with and without concurrent respiratory motion correction (MoCo).
MoCo PET/DCE-MRI of the upper abdomen was acquired in 44 consecutive oncologic patients and compared with non-MoCo PET/MRI. SUVmax and MTV of FDG-avid upper abdominal malignant lesions were assessed on MoCo and non-MoCo PET images. Image quality was compared between MoCo DCE-MRI and non-MoCo CE-MRI, and between fused MoCo PET/MRI and fused non-MoCo PET/MRI images.
MoCo PET resulted in higher SUVmax (10.8 ± 5.45) than non-MoCo PET (9.62 ± 5.42) and lower MTV (35.55 ± 141.95 cm) than non-MoCo PET (38.11 ± 198.14 cm; p < 0.005 for both). The quality of MoCo DCE-MRI images (4.73 ± 0.5) was higher than that of non-MoCo CE-MRI images (4.53±0.71; p = 0.037). The quality of fused MoCo-PET/MRI images (4.96 ± 0.16) was higher than that of fused non-MoCo PET/MRI images (4.39 ± 0.66; p < 0.005).
MoCo PET/MRI provided qualitatively better images than non-MoCo PET/MRI, and upper abdominal malignant lesions demonstrated higher SUVmax and lower MTV on MoCo PET/MRI.
比较上腹部 PET/DCE-MRI 伴呼吸运动校正（MoCo）与不伴呼吸运动校正（MoCo）的临床性能。
对 44 例连续的肿瘤患者进行上腹部 MoCo PET/DCE-MRI，并与非 MoCo PET/MRI 进行比较。评估 FDG 摄取的上腹部恶性病变在 MoCo 和非 MoCo PET 图像上的 SUVmax 和 MTV。比较 MoCo DCE-MRI 与非 MoCo CE-MRI、MoCo 融合 PET/MRI 与非 MoCo 融合 PET/MRI 图像之间的图像质量。
MoCo PET 的 SUVmax（10.8 ± 5.45）高于非 MoCo PET（9.62 ± 5.42），MTV（35.55 ± 141.95 cm）低于非 MoCo PET（38.11 ± 198.14 cm；p < 0.005）。MoCo DCE-MRI 图像的质量（4.73 ± 0.5）高于非 MoCo CE-MRI 图像（4.53 ± 0.71；p = 0.037）。MoCo 融合 PET/MRI 图像的质量（4.96 ± 0.16）高于非 MoCo 融合 PET/MRI 图像（4.39 ± 0.66；p < 0.005）。
MoCo PET/MRI 提供的图像质量优于非 MoCo PET/MRI，MoCo PET/MRI 上腹部恶性病变 SUVmax 较高，MTV 较低。
