No information is available on the clinical use of pegunigalsidase alfa during breastfeeding. Because pegunigalsidase alfa is a large protein molecule with a molecular weight of 116,000 Da, the amount in milk is likely to be very low.[1] It is also likely to be partially destroyed in the infant's gastrointestinal tract and absorption by the infant is probably minimal.[2] Polyethylene glycol is not excreted into breastmilk.[3] If pegunigalsidase alfa is required by the mother, it is not a reason to discontinue breastfeeding.
关于聚乙二醇化α-半乳糖苷酶在母乳喂养期间的临床应用尚无可用信息。由于聚乙二醇化α-半乳糖苷酶是一种分子量为116,000道尔顿的大蛋白质分子，乳汁中的含量可能非常低。[1]它也可能在婴儿胃肠道中被部分破坏，婴儿的吸收可能极少。[2]聚乙二醇不会排泄到母乳中。[3]如果母亲需要使用聚乙二醇化α-半乳糖苷酶，这不是停止母乳喂养的理由。
